The role of cell‐penetrating peptides in potential anti‐cancer therapy

M Zhou, X Zou, K Cheng, S Zhong, Y Su… - Clinical and …, 2022 - Wiley Online Library
Due to the complex physiological structure, microenvironment and multiple physiological
barriers, traditional anti‐cancer drugs are severely restricted from reaching the tumour site …

Recent advances in the development of EGFR degraders: PROTACs and LYTACs

D Hong, B Zhou, B Zhang, H Ren, L Zhu… - European Journal of …, 2022 - Elsevier
Abstract Epidermal Growth Factor Receptor (EGFR), a transmembrane tyrosine kinase
receptor, belongs to the ErbB receptor family, also known as HER1 or ErbB1. Its abnormal …

Emerging paradigms and recent progress in targeting ErbB in cancers

N Stoup, M Liberelle, N Lebègue… - Trends in …, 2024 - cell.com
The epidermal growth factor receptor (EGFR) family is a class of transmembrane proteins,
highly regarded as anticancer targets due to their pivotal role in various malignancies …

BR2 cell penetrating peptide effectively delivers anti-p21Ras scFv to tumor cells with ganglioside expression for therapy of ras-driven tumor

T Yu, Y Shi, X Pan, Q Feng, P Wang, S Song, L Yang… - Plos one, 2022 - journals.plos.org
Purpose Cell membrane penetrating peptide BR2 can bind with ganglioside and introduce
foreign drugs into tumor cells. In this study, we employed BR2 to carry the broad-spectrum …

Protein Delivery and Mimicry

Ü Langel - CPP, Cell-Penetrating Peptides, 2023 - Springer
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