Reactive oxygen species (ROS) are the key signaling molecules in many physiological
processes and play an important role in the development and function of the central nervous …

Stroke is a common disease with high mortality and disability worldwide. Different forms of
cell deaths, including apoptosis and necrosis, occur in ischemic or hemorrhagic brain tissue …

Alzheimer's disease (AD) is the most common form of dementia in the elderly, causing
neuronal degeneration and cognitive deficits that significantly impair independence and …

Either hypoxia in an acute ischemic stroke before thrombolysis or the oxygen-boost after
thrombolysis cause a high level of free radicals, resulting in successive injuries to …

Ischemic cerebral infarction represents a significant cause of disability and death worldwide.
Caspase-1 is activated by the NLRP3/ASC pathway and inflammasomes, thus triggering …

Neuroinflammation has been proven to exert an important effect on brain injury after
intracerebral hemorrhage (ICH). Previous studies reported that Didymin possessed anti …

Only a few types of inflammasomes have been described in central nervous system cells.
Among these, the absent in melanoma 2 (AIM2) inflammasome is primarily found in …

Recent work has indicated that photobiomodulation (PBM) may beneficially alter the
pathological status of several neurological disorders, although the mechanism currently …

Pyroptosis is an active and ordered form of programmed cell death. The signaling pathways
of pyroptosis are mainly divided into canonical pathways mediated by caspase-1 and …

Neonatal hypoxic-ischemic (HI) injury is a severe complication often leading to neonatal
death and long-term neurobehavioral deficits in children. Currently, the only treatment option …