In 1839, Professor Ancell recognized the properties of a protein vital to many functions in the
body. He wrote in Lancet,“albumen is doubtless one of the most important of the animal …

Publisher Summary This chapter presents albumin synthesis. Serum albumin is the major
protein produced in the liver, comprising as much as 50% of the productive effort at any one …

We have isolated and identified cDNA clones containing part of the coding sequence for rat
glyceraldehyde-3-phosphate-dehydrogenase (GAPDH, EC 1.2. 1.12). By using one of these …

Polysomes of rat liver appear to be either attached to the membrane of the endoplasmic
reticulum or free in the cytoplasm. It has been postulated that attached ribosomes are …

We have measured the rate of protein synthesis per unit of ribosomes in several tissues of
intact animals in the fed and fasted state. The technique utilized measured the rate of …

The effects of protein depletion and repletion on the rate of albumin synthesis and on the
levels of albumin in hepatic subcellular particles were measured in intact rats. A second …

SYNTHESIS of proteins from the mRNA in eukaryotic cells differs from prokaryotes in two
important ways. In the mammalian cell, the translation of mRNA in the cytoplasm is remote …

The serum albumin level is maintained by an effective balance between synthesis,
degradation, and distribution. The factors regulating albumin distribution are independent of …

Carbonate-14C was used to label the hepatic intracellular arginine pool and direct
measurement of albumin synthesis was made in six rabbits before and after an 18-36 hr fast …

The effects of amino acids on albumin synthesis were measured in 47 studies using the
isolated perfused rabbit liver. Carbon-14 carbonate was used to label the hepatic …