Besides their function in limiting blood loss and promoting wound healing, experimental
evidence has highlighted platelets as active players in all steps of tumorigenesis including …

Microparticles (MP) derived from vascular endothelium or circulating blood cells circulate in
the peripheral blood. They originate from blebbing and shedding from cell membrane …

Platelet activation leads to secretion of granule contents and to the formation of
microvesicles by shedding of membranes from the cell surface. Recently, we have described …

Platelets are conventionally defined as playing a vital role in homeostasis and thrombosis.
This role has over the years transformed as knowledge regarding platelets has expanded to …

The coronavirus pandemic has reportedly infected over 31.5 million individuals and caused
over 970,000 deaths worldwide (as of 22nd Sept 2020). This novel coronavirus, officially …

Although inflammation-induced thrombosis is a well-known entity, its pathogenesis remains
complicated. There are complex interactions between inflammation and hemostasis …

We used an immunoperoxidase procedure to examine the tissue distribution of the platelet
alpha-granule membrane protein, GMP-140. In addition to its presence in megakaryocytes …

We have investigated the composition and function of membrane microparticles released
from platelets exposed to the C5b-9 proteins of the complement system. Gel-filtered human …

Activation of human platelets by complement proteins C5b-9 is accompanied by the release
of small plasma membrane vesicles (microparticles) that are highly enriched in binding sites …

In the present study, we investigated whether high arterial shear stresses at various
exposure times or a sudden increase in shear stress introduced by a stenosis affect platelet …