Transfer RNA (tRNA) is an adapter molecule that links a specific codon in mRNA with its
corresponding amino acid during protein synthesis. tRNAs are enzymatically modified post …

5-methylcytosine (m5C) is an abundant RNA modification that's presence is reported in a
wide variety of RNA species, including cytoplasmic and mitochondrial ribosomal RNAs …

Mitochondria generate most cellular energy via oxidative phosphorylation. Twenty-two
species of mitochondrial (mt-) tRNAs encoded in mtDNA translate essential subunits of the …

Mitochondrial gene expression uses a non‐universal genetic code in mammals. Besides
reading the conventional AUG codon, mitochondrial (mt‐) tRNAM et mediates incorporation …

The principles of mRNA decoding are conserved among all extant life forms. We present an
integrative view of all the interaction networks between mRNA, tRNA and rRNA: the intrinsic …

In mammalian mitochondria, 22 species of tRNAs encoded in mitochondrial DNA play
crucial roles in the translation of 13 essential subunits of the respiratory chain complexes …

Abstract ALKBH1 is a 2-oxoglutarate-and Fe2+-dependent dioxygenase responsible for
multiple cellular functions. Here, we show that ALKBH1 is involved in biogenesis of 5 …

Rare tautomeric and anionic nucleobases are believed to have fundamental biological
roles, but their prevalence and functional importance has remained elusive because they …

ABSTRACT A simple post-transcriptional modification of tRNA, deamination of adenosine to
inosine at the first, or wobble, position of the anticodon, inspired Francis Crick's Wobble …

The genetic code that specifies the identity of amino acids incorporated into proteins during
protein synthesis is almost universally conserved. Mitochondrial genomes feature deviations …