Advancing the logic of chemical synthesis: C− H activation as strategic and tactical disconnections for C− C bond construction

NYS Lam, K Wu, JQ Yu - Angewandte Chemie, 2021 - Wiley Online Library
The design of synthetic routes by retrosynthetic logic is decisively influenced by the
transformations available. Transition‐metal‐catalyzed C− H activation has emerged as a …

Site-selective cross-coupling of polyhalogenated arenes and heteroarenes with identical halogen groups

V Palani, MA Perea, R Sarpong - Chemical reviews, 2021 - ACS Publications
Methods to functionalize arenes and heteroarenes in a site-selective manner are highly
sought after for rapidly constructing value-added molecules of medicinal, agrochemical, and …

Lamellarins and related pyrrole-derived alkaloids from marine organisms

H Fan, J Peng, MT Hamann, JF Hu - Chemical reviews, 2008 - ACS Publications
Marine organisms have proven to be rich sources of unique alkaloids. In earlier surveys we
comprehensively reviewed several intriguing groups of marine alkaloids, including the …

Replacing conventional carbon nucleophiles with electrophiles: nickel-catalyzed reductive alkylation of aryl bromides and chlorides

DA Everson, BA Jones, DJ Weix - Journal of the American …, 2012 - ACS Publications
A general method is presented for the synthesis of alkylated arenes by the chemoselective
combination of two electrophilic carbons. Under the optimized conditions, a variety of aryl …

Synthesis and biological activity of pyrrole, pyrroline and pyrrolidine derivatives with two aryl groups on adjacent positions

F Bellina, R Rossi - Tetrahedron, 2006 - Elsevier
Five-membered heterocycle derivatives with two aryl groups on adjacent positions include
several classes of natural and unnatural compounds that exhibit a variety of biological and …

Synthesis of natural products containing the pyrrolic ring

IS Young, PD Thornton, A Thompson - Natural product reports, 2010 - pubs.rsc.org
Synthesis of natural products containing the pyrrolic ring - Natural Product Reports (RSC
Publishing) DOI:10.1039/C0NP00014K Royal Society of Chemistry View PDF VersionPrevious …

Regioselective (site-selective) functionalisation of unsaturated halogenated nitrogen, oxygen and sulfur heterocycles by Pd-catalysed cross-couplings and direct …

IJS Fairlamb - Chemical Society Reviews, 2007 - pubs.rsc.org
This tutorial review focuses on several practical synthetic transformations utilising palladium
catalysis that facilitate the synthesis of functionalised unsaturated heterocycles in a …

An extremely active catalyst for the Negishi cross-coupling reaction

JE Milne, SL Buchwald - Journal of the American Chemical …, 2004 - ACS Publications
A new catalyst system for the Pd-catalyzed cross-coupling of organozinc reagents with aryl
halides (Negishi coupling) has been developed. This system permits efficient preparation of …

[PDF][PDF] Synthesis and biological activity of lamellarin alkaloids: an overview

M Iwao, T Fukuda, F Ishibashi - Heterocycles, 2011 - nagasaki-u.repo.nii.ac.jp
Lamellarins are natural products isolated from marine invertebrates having a unique
heterocyclic ring system. Many of these natural products exhibit potentially useful biological …

Lamellarin alkaloids: Isolation, synthesis, and biological activity

T Fukuda, F Ishibashi, M Iwao - The Alkaloids: Chemistry and Biology, 2020 - Elsevier
Lamellarins are marine alkaloids containing fused 14-phenyl-6H-[1] benzopyrano [4′, 3′:
4, 5] pyrrolo [2, 1-a] isoquinoline or non-fused 3, 4-diarylpyrrole-2-carboxylate ring systems …