Mitochondrial-targeted nanoparticles: Delivery and therapeutic agents in cancer

C Ganji, V Muppala, M Khan, GP Nagaraju… - Drug discovery today, 2023 - Elsevier
Highlights•Dysregulation of mitochondrial metabolism is a hallmark of cancer development.•
Nanoparticles (NPs) enable the efficient and targeted delivery of mitochondrial agents.•NPs …

Exploration of inorganic nanoparticles for revolutionary drug delivery applications: a critical review

G Unnikrishnan, A Joy, M Megha, E Kolanthai… - Discover Nano, 2023 - Springer
The nanosystems for delivering drugs which have evolved with time, are being designed for
greater drug efficiency and lesser side-effects, and are also complemented by the …

Green synthesis of ZnO-NPs using endophytic fungal extract of Xylaria arbuscula from Blumea axillaris and its biological applications

L Nehru, GD Kandasamy, V Sekar… - Artificial Cells …, 2023 - Taylor & Francis
The biogenic manufacture of nanoparticles utilising endophytic fungus is an eco-friendly,
cost-effective, and secure alternative to constructing chemical methods. The prime focus of …

Scaling-up strategies for controllable biosynthetic ZnO NPs using cell free-extract of endophytic Streptomycesalbus: characterization, statistical optimization, and …

SH El-Moslamy, MS Elnouby, AH Rezk… - Scientific Reports, 2023 - nature.com
In this study, we identified a suitable precursor and good cellular compartmentalization for
enhancing bioactive metabolites to produce biosynthetic zinc oxide nanoparticles (ZnO …

Methotrexate-conjugated zinc oxide nanoparticles exert a substantially improved cytotoxic effect on lung cancer cells by inducing apoptosis

P Mishra, MF Ali Ahmad, LA Al-Keridis… - Frontiers in …, 2023 - frontiersin.org
In the current study, we report the synthesis of methotrexate-conjugated zinc oxide
nanoparticles (MTX-ZnONPs) and their high efficacy against lung cancer cells. Conjugation …

Rubus Capped Zinc Oxide Nanoparticles Induce Apoptosis in MCF-7 Breast Cancer Cells

BP George, NK Rajendran, NN Houreld, H Abrahamse - Molecules, 2022 - mdpi.com
Rubus fairholmianus (RF) has widely been used to treat various ailments, including pain,
diabetes, and cancer. Zinc oxide nanoparticles (ZnO NPs) have drawn attention in modern …

Zinc Oxide Nanoparticles and Cancer Chemotherapy: Helpful Tools for Enhancing Chemo-sensitivity and Reducing Side Effects?

M Vaghari-Tabari, D Jafari-Gharabaghlou… - … Trace Element Research, 2024 - Springer
Cancer chemotherapy is still a serious challenge. Chemo-resistance and destructive side
effects of chemotherapy drugs are the most critical limitations of chemotherapy. Chemo …

Green synthesis of zinc oxide nanoparticles using egg white and coriander root waste: characterization and anti-cancer efficacy in Hela cells

M Saeed, LA Al-Keridis, S Khattak, L Alshuraym… - Waste and Biomass …, 2023 - Springer
In the present article, we employed an eco-friendly methodology for synthesizing zinc oxide
nanoparticles. We utilized a freshly derived combination of egg white and coriander root …

pH-Sensitive doxorubicin delivery using zinc oxide nanoparticles as a rectified theranostic platform: in vitro anti-proliferative, apoptotic, cell cycle arrest and in vivo …

MM Swidan, F Marzook, TM Sakr - Journal of Materials Chemistry B, 2024 - pubs.rsc.org
Despite enormous advancements in its management, cancer is the world's primary cause of
mortality. Therefore, tremendous strides were made to produce intelligent theranostics with …

Cytotoxicity of green synthesized zinc oxide nanoparticles using Musa acuminata on Vero cells

H Maheswaran, S Djearamane, ACTA Dhanapal… - Heliyon, 2024 - cell.com
Abstract Zinc oxide nanoparticles (ZnO NPs) have become a highly regarded substance in
various industries especially biologically synthesized ZnO NPs due to their adherence to the …