The CCL2-CCR2 axis is one of the major chemokine signaling pathways that has received
special attention because of its function in the development and progression of …

Chemokines are a family of cytokines that orchestrate the migration and positioning of
immune cells within tissues and are critical for the function of the immune system. CCR2 …

This review describes targeting neutrophils as a potential therapeutic strategy for acute
respiratory distress syndrome (ARDS) associated with coronavirus disease 2019 (COVID …

The acute respiratory distress syndrome (ARDS) is a life-threatening lung condition resulting
from direct and indirect insults to the lung. It is characterized by disruption of the endothelial …

Hypersensitivity pneumonia (HP) is an interstitial lung disease (ILD) caused by sensitization
to an inhaled antigen. Although the reported inciting antigens are numerous, most are …

ABSTRACT Introduction SARS-CoV-2, the causative agent of COVID-19, attacks the
immune system causing an exaggerated and uncontrolled release of pro-inflammatory …

Abstract Chemokine (CC motif) ligand 7 (CCL7), a CC chemokine, is a chemotactic factor
and attractant for various kinds of leukocytes, including monocytes and neutrophils. CCL7 is …

Idiopathic pulmonary fibrosis (IPF) is thought to result from aberrant tissue repair processes
in response to chronic or repetitive lung injury. The origin and nature of the injury, as well as …

Neutrophil influx into the extravascular compartments of the lungs is a defining characteristic
of the Acute Respiratory Distress Syndrome (ARDS). 1 During ARDS, circulating neutrophils …

Background Acute respiratory distress syndrome (ARDS) is a life-threatening condition
characterised by pulmonary oedema, respiratory failure and severe inflammation. ARDS is …