Mechanisms of 3D cell migration

KM Yamada, M Sixt - Nature Reviews molecular cell biology, 2019 - nature.com
Cell migration is essential for physiological processes as diverse as development, immune
defence and wound healing. It is also a hallmark of cancer malignancy. Thousands of …

Mechanisms and roles of podosomes and invadopodia

S Linder, P Cervero, R Eddy, J Condeelis - Nature Reviews Molecular …, 2023 - nature.com
Cell invasion into the surrounding extracellular matrix or across tissue boundaries and
endothelial barriers occurs in both physiological and pathological scenarios such as …

[HTML][HTML] Design the molecule structures to achieve functional advantages of hydrogel wound dressings: Advances and strategies

Z Zeng, M Zhu, L Chen, Y Zhang, T Lu, Y Deng… - Composites Part B …, 2022 - Elsevier
The wound healing and management are widely concerned in global military and civil
settings, which lays a huge public medical burden on the medical systems of every states …

[HTML][HTML] Mechanoresponsive metabolism in cancer cell migration and metastasis

MR Zanotelli, J Zhang, CA Reinhart-King - Cell metabolism, 2021 - cell.com
Altered tissue mechanics and metabolism are defining characteristics of cancer that impact
not only proliferation but also migration. While migrating through a mechanically and …

[HTML][HTML] CCL5/CCR5 axis in human diseases and related treatments

Z Zeng, T Lan, Y Wei, X Wei - Genes & diseases, 2022 - Elsevier
To defense harmful stimuli or maintain the immune homeostasis, the body produces and
recruits a superfamily of cytokines such as interleukins, interferons, chemokines etc. Among …

Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs

G Cirino, C Szabo… - Physiological …, 2023 - journals.physiology.org
Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …

The CCL5/CCR5 axis in cancer progression

D Aldinucci, C Borghese, N Casagrande - Cancers, 2020 - mdpi.com
Tumor cells can “hijack” chemokine networks to support tumor progression. In this context,
the CC chemokine ligand 5/CC chemokine receptor type 5 (CCL5/CCR5) axis is gaining …

Biomarker-targeted therapies for advanced-stage gastric and gastro-oesophageal junction cancers: an emerging paradigm

Y Nakamura, A Kawazoe, F Lordick… - Nature reviews Clinical …, 2021 - nature.com
Advances in cancer biology and sequencing technology have enabled the selection of
targeted and more effective treatments for individual patients with various types of solid …

In vitro Cell Migration, Invasion, and Adhesion Assays: From Cell Imaging to Data Analysis

J Pijuan, C Barceló, DF Moreno, O Maiques… - Frontiers in cell and …, 2019 - frontiersin.org
Cell migration is a key procedure involved in many biological processes including
embryological development, tissue formation, immune defense or inflammation, and cancer …

[HTML][HTML] GSDMB is increased in IBD and regulates epithelial restitution/repair independent of pyroptosis

N Rana, G Privitera, HC Kondolf, K Bulek, S Lechuga… - Cell, 2022 - cell.com
Gasdermins are a family of structurally related proteins originally described for their role in
pyroptosis. Gasdermin B (GSDMB) is currently the least studied, and while its association …