Amyloid oligomers: A joint experimental/computational perspective on Alzheimer's disease, Parkinson's disease, type II diabetes, and amyotrophic lateral sclerosis
PH Nguyen, A Ramamoorthy, BR Sahoo… - Chemical …, 2021 - ACS Publications
Protein misfolding and aggregation is observed in many amyloidogenic diseases affecting
either the central nervous system or a variety of peripheral tissues. Structural and dynamic …
either the central nervous system or a variety of peripheral tissues. Structural and dynamic …
Amyloid formation as a protein phase transition
The formation of amyloid fibrils is a general class of protein self-assembly behaviour, which
is associated with both functional biology and the development of a number of disorders …
is associated with both functional biology and the development of a number of disorders …
Half a century of amyloids: past, present and future
Amyloid diseases are global epidemics with profound health, social and economic
implications and yet remain without a cure. This dire situation calls for research into the …
implications and yet remain without a cure. This dire situation calls for research into the …
Impact of nanoparticles on amyloid peptide and protein aggregation: a review with a focus on gold nanoparticles
Society is increasingly exposed to nanoparticles as they are ubiquitous in nature and
introduced as man-made air pollutants and as functional ingredients in cosmetic products as …
introduced as man-made air pollutants and as functional ingredients in cosmetic products as …
Fundamentals of cross-seeding of amyloid proteins: an introduction
Misfolded protein aggregates formed by the same (homologous) or different
(heterologous/cross) sequences are the pathological hallmarks of many protein misfolding …
(heterologous/cross) sequences are the pathological hallmarks of many protein misfolding …
Graphene quantum dots against human IAPP aggregation and toxicity in vivo
The development of biocompatible nanomaterials has become a new frontier in the
detection, treatment and prevention of human amyloid diseases. Here we demonstrated the …
detection, treatment and prevention of human amyloid diseases. Here we demonstrated the …
Mitigation of amyloidosis with nanomaterials
Amyloidosis is a biophysical phenomenon of protein aggregation with biological and
pathogenic implications. Among the various strategies developed to date, nanomaterials …
pathogenic implications. Among the various strategies developed to date, nanomaterials …
[HTML][HTML] The role of surfaces on amyloid formation
F Grigolato, P Arosio - Biophysical Chemistry, 2021 - Elsevier
Interfaces can strongly accelerate or inhibit protein aggregation, destabilizing proteins that
are stable in solution or, conversely, stabilizing proteins that are aggregation-prone …
are stable in solution or, conversely, stabilizing proteins that are aggregation-prone …
Modulation of amyloid protein fibrillation by synthetic polymers: Recent advances in the context of neurodegenerative diseases
Protein misfolding and aggregation have attracted immense research interests due to their
connection with an array of degenerative diseases including neurodegenerative disorders …
connection with an array of degenerative diseases including neurodegenerative disorders …
Self-therapeutic nanomaterials: Applications in biology and medicine
Over past decades, nanotechnology has contributed to the biomedical field in areas
including detection, diagnosis, and drug delivery via opto-electronic properties or …
including detection, diagnosis, and drug delivery via opto-electronic properties or …