There is robust epidemiological evidence for the beneficial effects of broccoli consumption
on health, many of them clearly mediated by the isothiocyanate sulforaphane. Present in the …

There is substantial and promising evidence on the health benefits of consuming broccoli
and other cruciferous vegetables. The most important compound in broccoli, glucoraphanin …

Research into human biotransformation and elimination systems continues to evolve.
Various clinical and in vivo studies have been undertaken to evaluate the effects of foods …

Cruciferous vegetables are a rich source of glucosinolates and their hydrolysis products,
including indoles and isothiocyanates, and high intake of cruciferous vegetables has been …

Glucosinolates (GLSs) are found in Brassica vegetables. Examples of these sources include
cabbage, Brussels sprouts, broccoli, cauliflower and various root vegetables (eg radish and …

Commonly consumed foods and beverages can contain chemicals with reported
carcinogenic activity in rodent models. Moreover, exposures to some of these substances …

People's diet offers a greater and more diverse group of plant bioactives than do drugs, and
they often do not realise that many drugs are derived from the compounds originally …

Aromatic amines and heterocyclic aromatic amines (HAAs) are structurally related classes of
carcinogens that are formed during the combustion of tobacco or during the high …

Isothiocyanates from cruciferous vegetables have been studied extensively in cells and in
animals for their disease preventive and therapeutic effects. However, translating their utility …

Considerable support exists for the roles of metabolism in modulating the carcinogenic
properties of chemicals. In particular, many of these compounds are pro-carcinogens that …