The impact of NF-κB on inflammatory and angiogenic processes in age-related macular degeneration
WH Almalki, SS Almujri - Experimental Eye Research, 2024 - Elsevier
Age-related macular degeneration (AMD) is a prominent cause of vision loss, characterized
by two different types, dry (atrophic) and wet (neovascular). Dry AMD is distinguished by the …
by two different types, dry (atrophic) and wet (neovascular). Dry AMD is distinguished by the …
Multi-omics in exploring the pathophysiology of diabetic retinopathy
X Li, XJ Dong, W Zhang, Z Shi, Z Liu, Y Sa… - Frontiers in Cell and …, 2024 - frontiersin.org
Diabetic retinopathy (DR) is a leading global cause of vision impairment, with its prevalence
increasing alongside the rising rates of diabetes mellitus (DM). Despite the retina's complex …
increasing alongside the rising rates of diabetes mellitus (DM). Despite the retina's complex …
The role of lipid peroxidation in epithelial–mesenchymal transition of retinal pigment epithelial cells
W You, K Azuma, T Iwagawa, S Watanabe, M Aihara… - Scientific Reports, 2024 - nature.com
Abstract Epithelial–Mesenchymal Transition (EMT) of retinal pigment epithelial (RPE) cells is
recognized as pivotal in various retinal diseases. Previous studies have suggested a …
recognized as pivotal in various retinal diseases. Previous studies have suggested a …
Adrenomedullin 2/Intermedin Exerts Cardioprotective Effects by Regulating Cardiomyocyte Mitochondrial Function
Y Zhao, T Sakurai, A Kamiyoshi, M Tanaka… - …, 2024 - ahajournals.org
BACKGROUND: Adrenomedullin 2 (AM2) plays critical roles in regulating blood pressure
and fluid balance. However, the specific involvement of AM2 in cardiac hypertrophy has not …
and fluid balance. However, the specific involvement of AM2 in cardiac hypertrophy has not …
PI3Kδ Mediates Fibrosis by Patient-Derived Vitreous
D Liu, B Yan, Y Yin, F Chen, C Guo, Q Li, J Liu… - Laboratory …, 2024 - Elsevier
The epithelial-mesenchymal transition (EMT) is a fundamental process in developing fibrotic
diseases, including forming epiretinal membranes (ERMs). ERMs can result in irreversible …
diseases, including forming epiretinal membranes (ERMs). ERMs can result in irreversible …
An innovative rheology analysis method applies to the formulation optimization of Panax notoginseng total saponins ocular gel
H Xu, C Zang, F Zhang, J Tian, H Li… - Journal of Biomaterials …, 2024 - Taylor & Francis
Emphasizing the viscoelasticity of ophthalmic gels is crucial for understanding the residence
time, structure, and stability of hydrogels. This study primarily aimed to propose an …
time, structure, and stability of hydrogels. This study primarily aimed to propose an …
[HTML][HTML] Intermedin Alleviates Diabetic Cardiomyopathy by Up-Regulating CPT-1β through Activation of the Phosphatidyl Inositol 3 Kinase/Protein Kinase B Signaling …
J Zhao, L Han, YR Zhang, SM Liu, DR Ji, R Wang… - Pharmaceuticals, 2024 - mdpi.com
Diabetic cardiomyopathy (DCM), one of the most serious long-term consequences of
diabetes, is closely associated with myocardial fatty acid metabolism. Carnitine …
diabetes, is closely associated with myocardial fatty acid metabolism. Carnitine …
アドレノメデュリン2/インターメディンは心筋細胞のミトコンドリア機能を調節して心臓保護に働く
桜井敬之， 神吉昭子， 田中愛， 市川優佳， 河手久香… - 血管, 2024 - jstage.jst.go.jp
抄録 本稿では, カルシトニンスーパーファミリーに属する機能性ペプチドである, アドレノメデュリン 2
(AM2), 別名インターメジンの心臓および心筋細胞における役割を概説します. 我々は …
(AM2), 別名インターメジンの心臓および心筋細胞における役割を概説します. 我々は …