[HTML][HTML] Advances in research on type 2 diabetes mellitus targets and therapeutic agents

J Su, Y Luo, S Hu, L Tang, S Ouyang - International Journal of Molecular …, 2023 - mdpi.com
Diabetes mellitus is a chronic multifaceted disease with multiple potential complications, the
treatment of which can only delay and prolong the terminal stage of the disease, ie, type 2 …

Thyroid cancer and insulin resistance

G Brenta, F Di Fermo - Reviews in Endocrine and Metabolic Disorders, 2024 - Springer
Thyroid cancer has shown a parallel increase with diabetes in the last few years. This
narrative review aims to explain the association between these two entities, focusing on …

[HTML][HTML] Diabetes and obesity: the role of stress in the development of cancer

A Avogaro - Endocrine, 2024 - Springer
Diabesity is a condition where an individual has both diabetes and obesity, which can lead
to severe complications including cardiovascular disease, a leading cause of mortality …

[PDF][PDF] Extracellular MicroRNAs as Potential Biomarkers for Frail Kidney Phenotype: Progresses and Precautions

CT Chao, CK Chiang, KY Hung - Aging and disease, 2023 - scholar.archive.org
Frailty describes the cumulative subtle health deficits leading to an increased vulnerability to
insults among older individuals or disease-laden ones. The prevalence of frailty increases …

Applicability of mesenchymal stem cell-derived exosomes as a cell-free miRNA therapy and epigenetic modifiers for diabetes

S Sharma, R Bhonde - Epigenomics, 2023 - Taylor & Francis
Given that exosome nanovesicles constitute various growth factors, miRNAs and lncRNAs,
they have implications for epigenetic modifications. Few studies have shown that exosomes …

[HTML][HTML] Diabetes management in cancer patients. An Italian association of medical oncology, Italian association of medical Diabetologists, Italian Society of …

N Silvestris, T Franchina, M Gallo, A Argentiero… - ESMO open, 2023 - Elsevier
Highlights•This multidisciplinary consensus position paper focuses on identifying a novel
specialty field,'diabeto-oncology'.•A critical overview of cancer and diabetes co-management …

[HTML][HTML] The p66Shc Redox Protein and the Emerging Complications of Diabetes

G Biondi, N Marrano, A Borrelli, M Rella… - International Journal of …, 2023 - mdpi.com
Diabetes mellitus is a chronic metabolic disease, the prevalence of which is constantly
increasing worldwide. It is often burdened by disabling comorbidities that reduce the quality …

[HTML][HTML] Identifying miRNA Signatures Associated with Pancreatic Islet Dysfunction in a FOXA2-Deficient iPSC Model

AK Elsayed, N Aldous, NM Alajez… - Stem Cell Reviews and …, 2024 - Springer
The pathogenesis of diabetes involves complex changes in the expression profiles of mRNA
and non-coding RNAs within pancreatic islet cells. Recent progress in induced pluripotent …

[HTML][HTML] Ferroptosis and circular RNAs: new horizons in cancer therapy

AA Bhat, N Kukreti, M Afzal, A Goyal, R Thapa, H Ali… - EXCLI …, 2024 - ncbi.nlm.nih.gov
Cancer poses intricate challenges to treatment due to its complexity and diversity.
Ferroptosis and circular RNAs (circRNAs) are emerging as innovative therapeutic avenues …

[HTML][HTML] Glycemic control and cancer outcomes in oncologic patients with diabetes: an Italian Association of Medical Oncology (AIOM), Italian Association of Medical …

A Natalicchio, N Marrano, M Montagnani… - Journal of …, 2024 - Springer
Background: Increasing evidence suggests that diabetes increases the risk of developing
different types of cancer. Hyperinsulinemia, hyperglycemia and chronic inflammation …