COUP-TFII in health and disease
S Polvani, S Pepe, S Milani, A Galli - Cells, 2019 - mdpi.com
The nuclear receptors (NRs) belong to a vast family of evolutionary conserved proteins
acting as ligand-activated transcription factors. Functionally, NRs are essential in …
acting as ligand-activated transcription factors. Functionally, NRs are essential in …
Inflammation and DKK1-induced AKT activation contribute to endothelial dysfunction following NR2F2 loss
EJ Dougherty, LY Chen, KS Awad… - … of Physiology-Lung …, 2023 - journals.physiology.org
NR2F2 is expressed in endothelial cells (ECs) and Nr2f2 knockout produces lethal
cardiovascular defects. In humans, reduced NR2F2 expression is associated with …
cardiovascular defects. In humans, reduced NR2F2 expression is associated with …
Identification of novel genes and pathways regulated by the orphan nuclear receptor COUP-TFII in mouse MA-10 Leydig cells
S Mehanovic, RE Mendoza-Villarroel… - Biology of …, 2021 - academic.oup.com
In males, Leydig cells are the main producers of testosterone and insulin-like 3 (INSL3), two
hormones essential for sex differentiation and reproductive functions. Chicken ovalbumin …
hormones essential for sex differentiation and reproductive functions. Chicken ovalbumin …
NR2F2 orphan nuclear receptor is involved in estrogen receptor alpha-mediated transcriptional regulation in luminal a breast cancer cells
Nuclear Receptor Subfamily 2 Group F Member 2 (NR2F2) is a member of the
steroid/thyroid hormone receptor superfamily with a crucial role in organogenesis …
steroid/thyroid hormone receptor superfamily with a crucial role in organogenesis …
The Coup-TFII orphan nuclear receptor is an activator of the γ-globin gene
C Fugazza, G Barbarani, S Elangovan… - …, 2020 - pmc.ncbi.nlm.nih.gov
The human fetal γ-globin gene is repressed in adulthood through complex regulatory
mechanisms involving transcription factors and epigenetic modifiers. Reversing γ-globin …
mechanisms involving transcription factors and epigenetic modifiers. Reversing γ-globin …
Kruppel-Like Factor 5 Regulates Expression of Key Genes in Human Airway Epithelial Cells, Including CFTR
A Paranjapye - 2022 - search.proquest.com
The essential biological functions of the airway epithelium are regulated by a hierarchy of
transcription factors. Amongst these is Krüppel-like Factor 5 (KLF5), a member of a family of …
transcription factors. Amongst these is Krüppel-like Factor 5 (KLF5), a member of a family of …
[PDF][PDF] Steroids induced cytotoxicity in hepatic cancer cells
INA Al-Ibadi, AK Alhatemi, MM Meteab - researchgate.net
Hepatic cancer or Hepatocellular carcinoma is a common tumor of liver, in particular
between males and it known as a most fatal cancer between others. The usual therapy is …
between males and it known as a most fatal cancer between others. The usual therapy is …