Astrocyte reactivity: subtypes, states, and functions in CNS innate immunity

MV Sofroniew - Trends in immunology, 2020 - cell.com
Astrocytes are neural parenchymal cells that ubiquitously tile the central nervous system
(CNS). In addition to playing essential roles in healthy tissue, astrocytes exhibit an …

Advances in skin regeneration using tissue engineering

K Vig, A Chaudhari, S Tripathi, S Dixit, R Sahu… - International journal of …, 2017 - mdpi.com
Tissue engineered skin substitutes for wound healing have evolved tremendously over the
last couple of years. New advances have been made toward developing skin substitutes …

Self-powered enzyme-linked microneedle patch for scar-prevention healing of diabetic wounds

X Zhang, Z Wang, H Jiang, H Zeng, N An, B Liu… - Science …, 2023 - science.org
Diabetic wounds with complex pathological features and a difficult-to-heal nature remain a
formidable challenge. To address this challenge, we design and fabricate a self-powered …

3D printed piezoelectric wound dressing with dual piezoelectric response models for scar-prevention wound healing

J Liang, H Zeng, L Qiao, H Jiang, Q Ye… - … applied materials & …, 2022 - ACS Publications
During the long process of wound defect repair, the bioelectric stimulation around the wound
gradually decreases, which can cause gradual down-regulation of the wound healing …

Exosomes secreted by human adipose mesenchymal stem cells promote scarless cutaneous repair by regulating extracellular matrix remodelling

L Wang, L Hu, X Zhou, Z Xiong, C Zhang… - Scientific Reports, 2017 - nature.com
Scar formation is an intractable medical problem that appears after skin wounds have
healed. Recent research has shown that exosomes secreted by human adipose …

[HTML][HTML] Controlled water vapor transmission rate promotes wound-healing via wound re-epithelialization and contraction enhancement

R Xu, H Xia, W He, Z Li, J Zhao, B Liu, Y Wang, Q Lei… - Scientific reports, 2016 - nature.com
A desirable microenvironment is essential for wound healing, in which an ideal moisture
content is one of the most important factors. The fundamental function and requirement for …

In situ formed anti-inflammatory hydrogel loading plasmid DNA encoding VEGF for burn wound healing

P Wang, S Huang, Z Hu, W Yang, Y Lan, J Zhu… - Acta biomaterialia, 2019 - Elsevier
Excessive inflammation and reduced angiogenesis are two major obstacles in burn wound
healing and skin regeneration. Here we report the fabrication and application of a …

Mesenchymal stromal cells and cutaneous wound healing: a comprehensive review of the background, role, and therapeutic potential

MS Hu, MR Borrelli, HP Lorenz… - Stem cells …, 2018 - Wiley Online Library
Cutaneous wound repair is a highly coordinated cascade of cellular responses to injury
which restores the epidermal integrity and its barrier functions. Even under optimal healing …

Fibroblast heterogeneity and its implications for engineering organotypic skin models in vitro

G Sriram, PL Bigliardi, M Bigliardi-Qi - European journal of cell biology, 2015 - Elsevier
Advances in cell culture methods, multidisciplinary research, clinical need to replace lost
skin tissues and regulatory need to replace animal models with alternative test methods has …

Advances of stem cell therapeutics in cutaneous wound healing and regeneration

S Kanji, H Das - Mediators of inflammation, 2017 - Wiley Online Library
Cutaneous wound healing is a complex multiple phase process, which overlaps each other,
where several growth factors, cytokines, chemokines, and various cells interact in a well …