Near-infrared (NIR) fluorophores have unique features that endow them with several
advantages over conventional shorter wavelength emitting dyes. As a result, they have been …

Synthetic 3D extracellular matrices (ECMs) find application in cell studies, regenerative
medicine, and drug discovery. While cells cultured in a monolayer may exhibit unnatural …

Polarity, as a complex parameter, plays pivotal roles in chemistry and biology. Deviant
polarity change in different subcellular compartments is closely connected with diseases …

Cancer is a multistep disease driven by the activation of specific oncogenic pathways
concomitantly with the loss of function of tumor suppressor genes that act as sentinels to …

Mitochondrial dysfunction is a hallmark of many diseases. The retrograde signaling initiated
by dysfunctional mitochondria can bring about global changes in gene expression that alters …

Intracellular peroxynitrite anions (ONOO–) and microenvironments (such as viscosity and
polarity) play an important role in maintaining redox homeostasis, regulating diffusion …

Cancer is a worldwide health problem. Revealing the changes in the microenvironment after
cell carcinogenesis is helpful to understand cancer and develop sensitive methods for …

Intracellular hydrogen sulfide (H 2 S) and micro-environments (eg viscosity and polarity) are
tightly correlated with various physiological/pathological processes, making them potential …

After years of extensive scientific discovery much has been learned about the networks that
regulate epithelial homeostasis. Loss of expression or functional activity of cell adhesion …

The embryonic program 'epithelial-mesenchymal transition'(EMT) is activated during tumor
invasion in disseminating cancer cells. Characteristic to these cells is a loss of E-cadherin …