Integration of network models and evolutionary analysis into high-throughput modeling of protein dynamics and allosteric regulation: theory, tools and applications
Proteins are dynamical entities that undergo a plethora of conformational changes,
accomplishing their biological functions. Molecular dynamics simulation and normal mode …
accomplishing their biological functions. Molecular dynamics simulation and normal mode …
Every protagonist has a sidekick: Structural aspects of human xeroderma pigmentosum‐binding proteins in nucleotide excision repair
BC Feltes - Protein Science, 2021 - Wiley Online Library
The seven xeroderma pigmentosum proteins (XPps), XPA–XPG, coordinate the nucleotide
excision repair (NER) pathway, promoting the excision of DNA lesions caused by exposition …
excision repair (NER) pathway, promoting the excision of DNA lesions caused by exposition …
Proteomic analysis of nuclear hepatitis B virus relaxed circular DNA-associated proteins identifies UV-damaged DNA binding protein as a host factor involved in …
AL Marchetti, H Zhang, ES Kim, X Yu, S Jang… - Journal of …, 2022 - Am Soc Microbiol
Hepatitis B virus (HBV) utilizes host DNA repair mechanisms to convert viral relaxed circular
DNA (rcDNA) into a persistent viral genome, the covalently closed circular DNA (cccDNA) …
DNA (rcDNA) into a persistent viral genome, the covalently closed circular DNA (cccDNA) …
The nucleotide excision repair proteins through the lens of molecular dynamics simulations
Mutations that affect the proteins responsible for the nucleotide excision repair (NER)
pathway can lead to diseases such as xeroderma pigmentosum, trichothiodystrophy …
pathway can lead to diseases such as xeroderma pigmentosum, trichothiodystrophy …
[HTML][HTML] Revisiting the structural features of the xeroderma pigmentosum proteins: Focus on mutations and knowledge gaps
BC Feltes - Mutation Research/Reviews in Mutation Research, 2022 - Elsevier
The nucleotide excision repair pathway is a broadly studied DNA repair mechanism
because impairments of its key players, the xeroderma pigmentosum proteins (XPA to XPG) …
because impairments of its key players, the xeroderma pigmentosum proteins (XPA to XPG) …
NIAS‐Server 2.0: A versatile complementary tool for structural biology studies
BC Feltes, ÉSM Pinto, AT Mangini… - Journal of …, 2023 - Wiley Online Library
Increasing the repertoire of available complementary tools to advance the knowledge of
protein structures is fundamental for structural biology. The Neighbors Influence of Amino …
protein structures is fundamental for structural biology. The Neighbors Influence of Amino …
Novel mutation identified in the DDB2 gene in patients with xeroderma pigmentosum group–E
E Karagün, R Eroz, M Gamsızkan… - International Journal …, 2020 - Wiley Online Library
Background Xeroderma pigmentosum (XP) is a rare photosensitive syndrome, which is
divided into eight complementation groups (XP‐A to XP‐G and XPV) and characterized by …
divided into eight complementation groups (XP‐A to XP‐G and XPV) and characterized by …
[图书][B] Proteomic Analysis of Nuclear HBV rcDNA Associated Proteins Identifies UV-DDB as a Host Factor Involved in cccDNA Formation
AL Marchetti - 2022 - search.proquest.com
Despite the lifecycle of the hepatitis B virus (HBV) being extensively investigated and
described, there remains a significant gap in our knowledge of arguably one of the most …
described, there remains a significant gap in our knowledge of arguably one of the most …
[HTML][HTML] 拮抗剂方案中应用GnRHa 扳机与hCG 扳机对妊娠结局的影响
邢泽， 焦娇， 孙弘昊， 王秀霞 - 中国医科大学学报, 2021 - html.rhhz.net
目的研究拮抗剂方案中应用促性腺激素释放激素激动剂(GnRHa) 扳机与人绒毛膜促性腺激素(
hCG) 扳机对患者胚胎质量和妊娠结局的影响. 方法本研究为前瞻性研究, 选择于我院接受体外 …
hCG) 扳机对患者胚胎质量和妊娠结局的影响. 方法本研究为前瞻性研究, 选择于我院接受体外 …
[HTML][HTML] DDB2基因不同转录本在胃癌和正常胃组织中的表达差异及其对胃癌细胞增殖的影响
郑博文， 刘经纬， 孙丽萍， 邢承忠 - 中国医科大学学报, 2021 - html.rhhz.net
目的探讨DDB2 基因不同转录本在胃癌和远端正常胃组织中的表达差异及其对胃癌细胞增殖的
影响. 方法提取22 对胃癌和远端正常胃组织的总RNA, 利用实时定量PCR (RT-qPCR) …
影响. 方法提取22 对胃癌和远端正常胃组织的总RNA, 利用实时定量PCR (RT-qPCR) …