The pathogenesis of Nipah virus: A review

P Devnath, S Wajed, RC Das, S Kar, I Islam… - Microbial …, 2022 - Elsevier
Nipah virus (NiV), an emerging zoonotic virus, has been associated with several outbreaks
with high death rates, mainly in South and Southeast Asia. NiV is responsible for …

Structures of the Mononegavirales Polymerases

B Liang - Journal of Virology, 2020 - Am Soc Microbiol
Mononegavirales, known as nonsegmented negative-sense (NNS) RNA viruses, are a class
of pathogenic and sometimes deadly viruses that include rabies virus (RABV), human …

Initiation, extension, and termination of RNA synthesis by a paramyxovirus polymerase

PC Jordan, C Liu, P Raynaud, MK Lo… - PLoS …, 2018 - journals.plos.org
Paramyxoviruses represent a family of RNA viruses causing significant human diseases.
These include measles virus, the most infectious virus ever reported, in addition to …

Cryo-EM structure of the respiratory syncytial virus RNA polymerase

D Cao, Y Gao, C Roesler, S Rice, P D'Cunha… - Nature …, 2020 - nature.com
The respiratory syncytial virus (RSV) RNA polymerase, constituted of a 250 kDa large (L)
protein and tetrameric phosphoprotein (P), catalyzes three distinct enzymatic activities …

Structure of a paramyxovirus polymerase complex reveals a unique methyltransferase-CTD conformation

R Abdella, M Aggarwal, T Okura… - Proceedings of the …, 2020 - National Acad Sciences
Paramyxoviruses are enveloped, nonsegmented, negative-strand RNA viruses that cause a
wide spectrum of human and animal diseases. The viral genome, packaged by the …

Pseudotyping lentiviral vectors: when the clothes make the virus

A Duvergé, M Negroni - Viruses, 2020 - mdpi.com
Delivering transgenes to human cells through transduction with viral vectors constitutes one
of the most encouraging approaches in gene therapy. Lentivirus-derived vectors are among …

Formation and function of liquid-like viral factories in negative-sense single-stranded RNA virus infections

JM Su, MZ Wilson, CE Samuel, D Ma - Viruses, 2021 - mdpi.com
Liquid–liquid phase separation (LLPS) represents a major physiochemical principle to
organize intracellular membrane-less structures. Studies with non-segmented negative …

Phylogeography, transmission, and viral proteins of Nipah virus

B Sun, L Jia, B Liang, Q Chen, D Liu - Virologica Sinica, 2018 - Springer
Nipah virus (NiV), a zoonotic paramyxovirus belonging to the genus Henipavirus, is
classified as a Biosafety Level-4 pathogen based on its high pathogenicity in humans and …

An ultraweak interaction in the intrinsically disordered replication machinery is essential for measles virus function

S Milles, MR Jensen, C Lazert, S Guseva… - Science …, 2018 - science.org
Measles virus genome encapsidation is essential for viral replication and is controlled by the
intrinsically disordered phosphoprotein (P) maintaining the nucleoprotein in a monomeric …

Structure, dynamics and phase separation of measles virus RNA replication machinery

S Guseva, S Milles, MR Jensen, G Schoehn… - Current opinion in …, 2020 - Elsevier
The measles virus replication complex represents a potentially important, but as yet
relatively unexplored target for viral inhibition. Little is known about the molecular …