Epithelial‐mesenchymal transition (EMT) is a complex process with a primordial role in
cellular transformation whereby an epithelial cell transforms and acquires a mesenchymal …

Epithelial-mesenchymal transition (EMT) is a crucial, evolutionarily conserved process that
occurs during development and is essential for shaping embryos. Also implicated in cancer …

Aberrant cell signaling can cause cancer and other diseases and is a focal point of drug
research. A common approach is to infer signaling activity of pathways from gene …

Cancer is a complex multistep process involving genetic and epigenetic changes that
eventually result in the activation of oncogenic pathways and/or inactivation of tumor …

A steadily growing number of studies have shown that microRNAs have key roles in the
regulation of cellular processes and that their dysregulation is essential to keep the …

Metastatic cancer cells are lethal. Understanding the molecular mechanisms that bolster the
conversion from benign to malignant progression is key for treating these heterogeneous …

Among deregulated microRNAs (miRs) in human malignancies, miR-221 has been widely
investigated for its oncogenic role and as a promising biomarker. Moreover, recent evidence …

The epithelial to mesenchymal transition (EMT) is a powerful process in tumor invasion,
metastasis, and tumorigenesis and describes the molecular reprogramming and phenotypic …

The epithelial-mesenchymal transition program becomes activated during malignant
progression and can enrich for cancer stem cells (CSCs). We report that inhibition of protein …

The transition from ductal carcinoma in situ to invasive ductal carcinoma is a key event in
breast cancer progression that is still not well understood. To discover the microRNAs …