Platelets are small anucleate blood cells generated from megakaryocytes in the bone
marrow and cleared in the reticuloendothelial system. At the site of vascular injury, platelet …

Extensive experimental evidence shows that platelets support tumour metastasis. The
activation of platelets and the coagulation system have a crucial role in the progression of …

Disease progression in cancer is dependent on the complex interaction between the tumor
and the host inflammatory response. There is substantial evidence in advanced cancer that …

The hemostatic system is often subverted in patients with cancer, resulting in life-threatening
venous thrombotic events. Despite the multifactorial and complex etiology of cancer …

Background Although thrombocytosis has been reported in patients with various types of
cancer, the association between thrombocytosis and the clinicopathological features of …

It has long been recognised that the function of platelets in health and disease span far
beyond their roles in haemostasis and thrombosis. The observation that tumour cells induce …

Platelets are a class of pluripotent cells that, in addition to hemostasis and maintaining
vascular endothelial integrity, are also involved in tumor growth and distant metastasis. The …

Cancer is still a leading cause of death worldwide and liquid biopsy is a powerful tool that
can be applied to different stages of cancer screening and treatment. However, as the …

The main function of circulating platelets is to stop bleeding upon vascular injury by the
formation of a hemostatic plug. The presence of cancer results in numerical and functional …

Despite the fact that malignancies are associated with hematological abnormalities, some
clinical studies have been unable to detect such a relation. The aim of our study was to …