Regulation of Precise DNA Repair by Nuclear Actin Polymerization: A Chance for Improving Gene Therapy?

X He, C Brakebusch - Cells, 2024 - mdpi.com
Although more difficult to detect than in the cytoplasm, it is now clear that actin
polymerization occurs in the nucleus and that it plays a role in the specific processes of the …

Chromatin modifiers in human disease: from functional roles to regulatory mechanisms

Y Nie, C Song, H Huang, S Mao, K Ding, H Tang - Molecular Biomedicine, 2024 - Springer
The field of transcriptional regulation has revealed the vital role of chromatin modifiers in
human diseases from the beginning of functional exploration to the process of participating …

The mechanism of INO80D involved in chromatin remodeling regulating spermatogenesis in Chinese mitten crab (Eriocheir sinensis)

Y Mo, L Sun, S Li, L Luo, H Liu, S Huang… - Molecular Genetics and …, 2024 - Springer
The INO80D protein, a component of the INO80 chromatin remodeling complex, plays a
pivotal role in chromatin remodeling, gene expression, and DNA repair within mammalian …

Structural and Biochemical Characterization of the Nucleosome Containing Variants H3. 3 and H2A. Z

H Jung, V Sokolova, G Lee, VR Stevens, D Tan - Epigenomes, 2024 - mdpi.com
Variant H3. 3, along with H2A. Z, is notably enriched at promoter regions and is commonly
associated with transcriptional activation. However, the specific molecular mechanisms …