Aliphatic polycarbonates from cyclic carbonate monomers and their application as biomaterials

W Yu, E Maynard, V Chiaradia, MC Arno… - Chemical …, 2021 - ACS Publications
Aliphatic polycarbonates have gained increased attention as biomaterials largely owing to
their biocompatibility and tunable degradation. Moreover, the ability to introduce functional …

Enabling New Approaches: Recent Advances in Processing Aliphatic Polycarbonate‐Based Materials

P Wei, GA Bhat, DJ Darensbourg - … Chemie International Edition, 2023 - Wiley Online Library
Aliphatic polycarbonates (aPCs) have become increasingly popular as functional materials
due to their biocompatibility and capacity for on‐demand degradation. Advances in …

Poly (trimethylene carbonate)-based polymers engineered for biodegradable functional biomaterials

K Fukushima - Biomaterials science, 2016 - pubs.rsc.org
Aliphatic polycarbonates have drawn attention as biodegradable polymers that can be
applied to a broad range of resorbable medical devices. In particular, poly (trimethylene …

An iRGD-conjugated prodrug micelle with blood-brain-barrier penetrability for anti-glioma therapy

L Lu, X Zhao, T Fu, K Li, Y He, Z Luo, L Dai, R Zeng… - Biomaterials, 2020 - Elsevier
Various obstacles impede the chemotherapy efficiency of glioma in clinic, such as blood
brain barrier (BBB) and blood brain tumor barrier (BBTB). Ligand-mediated polymeric …

Co-delivery of drugs and plasmid DNA for cancer therapy

PY Teo, W Cheng, JL Hedrick, YY Yang - Advanced drug delivery reviews, 2016 - Elsevier
Cancer is an extremely complex disease involving multiple signaling pathways that enable
tumor cells to evade programmed cell death, thus making cancer treatment extremely …

PH responsive polyurethane for the advancement of biomedical and drug delivery

RYH Tan, CS Lee, MR Pichika, SF Cheng, KY Lam - Polymers, 2022 - mdpi.com
Due to the specific physiological pH throughout the human body, pH-responsive polymers
have been considered for aiding drug delivery systems. Depending on the surrounding pH …

High co-loading capacity and stimuli-responsive release based on cascade reaction of self-destructive polymer for improved chemo-photodynamic therapy

M Wang, Y Zhai, H Ye, Q Lv, B Sun, C Luo, Q Jiang… - ACS …, 2019 - ACS Publications
Photodynamic therapy (PDT) shows a promising synergy with chemotherapy in the
therapeutic outcome of malignant cancers. The minimal invasiveness and nonsystemic …

Polymeric nanomedicines for the treatment of hepatic diseases

F Luo, Y Yu, M Li, Y Chen, P Zhang, C Xiao… - Journal of …, 2022 - Springer
The liver is an important organ in the human body and performs many functions, such as
digestion, detoxification, metabolism, immune responses, and vitamin and mineral storage …

Photosensitizer enhanced disassembly of amphiphilic micelle for ROS-response targeted tumor therapy in vivo

L Dai, Y Yu, Z Luo, M Li, W Chen, X Shen, F Chen… - Biomaterials, 2016 - Elsevier
This study reports a reactive oxygen species (ROS) sensitive drug delivery system based on
amphiphilic polymer of poly (propylene sulfide)-polyethylene glycol-serine-folic acid (PPS …

Dual targeting of l-carnitine-conjugated nanoparticles to OCTN2 and ATB0,+ to deliver chemotherapeutic agents for colon cancer therapy

L Kou, Q Yao, S Sivaprakasam, Q Luo, Y Sun, Q Fu… - Drug Delivery, 2017 - Taylor & Francis
Abstract l-Carnitine, obligatory for oxidation of fatty acids, is transported into cells by the Na+-
coupled transporter OCTN2 and the Na+/Cl–-coupled transporter ATB0,+. Here we …