N Nikolaus, B Strehlitz - Microchimica Acta, 2008 - Springer
The article reviews the use of electrochemical biosensors for detecting lactate, a key metabolite of the anaerobic glycolytic pathway. This compound plays an important role in …
M Ciobanu, DE Taylor, JP Wilburn… - Analytical chemistry, 2008 - ACS Publications
We have developed glucose and lactate ultramicroelectrode (UME) biosensors based on glucose oxidase and lactate oxidase (with enzymes immobilized onto Pt UMEs by either …
K Dagar, CS Pundir - Enzyme and microbial technology, 2017 - Elsevier
An improved amperometric l-lactate biosensor was constructed based on covalent immobilization of lactate oxidase (LOx) from Pediococcus species onto carboxylated …
NF Shram, LI Netchiporouk, C Martelet… - Analytical …, 1998 - ACS Publications
To allow rat brain lactate measurement in vivo, a specific sensor based on a carbon fiber (ϕ= 30 μm) microelectrode coated with lactate oxidase was prepared. Combined with the …
Lactate is widely measured in critically ill patients as a robust indicator of patient deterioration and response to treatment. Plasma concentrations represent a balance …
A reagentless lactate amperometric biosensor, constructed by immobilising the enzymes glutamic pyruvic transaminase (GPT) and l-lactate dehydrogenase (LDH) together with its …
N Hamamatsu, Y Nomiya, T Aita… - Protein Engineering …, 2006 - academic.oup.com
We assumed that adverse effects posed by introducing multiple mutations could be decomposed into those of each of the component mutations and that the risk could be …
H Minagawa, N Nakayama, T Matsumoto… - Biosensors and …, 1998 - Elsevier
We examined a long life lactate sensor that employs two types of thermostable mutant lactate oxidase, both generated by random mutagenesis. One of the mutants, LOD15 …
A new method for the determination of lactic acid based on the immobilization enzyme fluorescence capillary analysis (IE-FCA) was proposed. Lactic dehydrogenase (LDH) was …