Over the past decade there has been an increasing reliance on strong opioids to treat acute
and chronic pain, which has been associated with a rising epidemic of prescription opioid …

Opioids are a mainstay of acute pain management but can have many adverse effects,
contributing to problematic long-term use. Opioid tolerance (increased dose needed for …

Implantable devices capable of targeted and reversible blocking of peripheral nerve activity
may provide alternatives to opioids for treating pain. Local cooling represents an attractive …

Opioids form an important component of general anesthesia and perioperative analgesia.
Discharge opioid prescriptions are identified as a contributor for persistent opioid use and …

Background One in 16 surgical patients prescribed opioids becomes a long-term user.
Overprescribing opioids after surgery is common, and the lack of multidisciplinary procedure …

Importance Prolonged opioid use after surgery may be associated with opioid dependency
and increased health care use. However, published studies have reported varying estimates …

Background Inadequate pain management after surgery increases the risk of postoperative
complications and may predispose for chronic postsurgical pain. Perioperative ketamine …

This international multidisciplinary consensus statement was developed to provide balanced
guidance on the safe peri‐operative use of opioids in adults. An international panel of …

Importance Opioids administered to treat postsurgical pain are a major contributor to the
opioid crisis, leading to chronic use in a considerable proportion of patients. Initiatives …

Objective: The International Patterns of Opioid Prescribing study compares postoperative
opioid prescribing patterns in the United States (US) versus the rest of the world. Summary …