Recent advances in acid sensing by G protein coupled receptors

MD Glitsch - Pflügers Archiv-European Journal of Physiology, 2024 - Springer
Abstract Changes in extracellular proton concentrations occur in a variety of tissues over a
range of timescales under physiological conditions and also accompany virtually all …

Neuroimmune mechanisms in fear and panic pathophysiology

KMJ McMurray, R Sah - Frontiers in Psychiatry, 2022 - frontiersin.org
Panic disorder (PD) is unique among anxiety disorders in that the emotional symptoms (eg,
fear and anxiety) associated with panic are strongly linked to body sensations indicative of …

Projections from subfornical organ to bed nucleus of the stria terminalis modulate inflammation-induced anxiety-like behaviors in mice

J Zhang, C Xie, P Xu, Q Tong, L Xiao, J Zhong - Science Advances, 2024 - science.org
Peripheral inflammation is closely related to the pathogenesis of sickness behaviors and
psychiatric disorders such as anxiety and depression. The circumventricular organs (CVOs) …

Microglial reactivity in brainstem chemosensory nuclei in response to hypercapnia

J Eugenín, S Beltrán-Castillo, E Irribarra… - Frontiers in …, 2024 - frontiersin.org
Microglia, the resident immune cells of the CNS, surveil, detect, and respond to various
extracellular signals. Depending on the nature of these signals, an integrative microglial …

Regulator of G protein signalling 14 (RGS14) protein expression profile in the adult mouse brain

SN Bramlett, SM Fitzmaurice, NH Harbin… - European Journal of …, 2024 - Wiley Online Library
Regulator of G protein signalling 14 (RGS14) is a multifunctional signalling protein that
serves as a natural suppressor of synaptic plasticity in the mouse brain. Our previous studies …

Phenotypic and Functional Alterations in Peripheral Blood Mononuclear Cell-Derived Microglia in a Primate Model of Chronic Alcohol Consumption

H Hemati, MB Blanton, HE True, J Koura, R Khadka… - bioRxiv, 2025 - biorxiv.org
Alcohol-induced dysregulation of microglial activity is associated with neuroinflammation,
cognitive decline, heightened risk for neurodegenerative diseases, alcohol dependence …

From Airway inflammation to Fear: Potential role of T helper cells-Interleukin 17A (IL-17A) and the subfornical organ (SFO)

EN Allgire - 2024 - search.proquest.com
Abstract Posttraumatic Stress Disorder (PTSD) is a highly prevalent psychiatric disorder.
Inflammation, and specifically severe asthma, has been implicated in PTSD through genetic …