BACKGROUND Blood and lymphatic vessel networks form two arms of the vertebrate cardiovascular system that play complementary roles in body homeostasis maintenance and …
LC Dieterich, C Tacconi, L Ducoli… - Physiological …, 2022 - journals.physiology.org
The lymphatic system, composed of initial and collecting lymphatic vessels as well as lymph nodes that are present in almost every tissue of the human body, acts as an essential …
T Mäkinen, LM Boon, M Vikkula, K Alitalo - Circulation research, 2021 - Am Heart Assoc
Lymphatic vessels maintain tissue fluid homeostasis by returning to blood circulation interstitial fluid that has extravasated from the blood capillaries. They provide a trafficking …
The lymphatic system is comprised of a network of vessels interrelated with lymphoid tissue, which has the holistic function to maintain the local physiologic environment for every cell in …
M Potente, T Mäkinen - Nature Reviews Molecular Cell Biology, 2017 - nature.com
Blood and lymphatic vessels pervade almost all body tissues and have numerous essential roles in physiology and disease. The inner lining of these networks is formed by a single …
S Karaman, VM Leppänen, K Alitalo - Development, 2018 - journals.biologists.com
Vascular endothelial growth factors (VEGFs) are best known for their involvement in orchestrating the development and maintenance of the blood and lymphatic vascular …
EA Korhonen, A Murtomäki, SK Jha… - The Journal of …, 2022 - Am Soc Clin Investig
Vascular endothelial growth factor C (VEGF-C) induces lymphangiogenesis via VEGF receptor 3 (VEGFR3), which is encoded by the most frequently mutated gene in human …
S Antila, S Karaman, H Nurmi, M Airavaara… - Journal of Experimental …, 2017 - rupress.org
The recent discovery of meningeal lymphatic vessels (LVs) has raised interest in their possible involvement in neuropathological processes, yet little is known about their …
The mammalian circulatory system comprises both the cardiovascular system and the lymphatic system. In contrast to the blood vascular circulation, the lymphatic system forms a …