Biomimetic hydrogels designed for cartilage tissue engineering

KD Ngadimin, A Stokes, P Gentile, AM Ferreira - Biomaterials science, 2021 - pubs.rsc.org
Cartilage regeneration and repair remain a clinical challenge due to the limited capability of
cartilage to self-regenerate. Worldwide, the costs associated with cartilage regeneration per …

A review of adaptive mechanisms in cell responses towards oxidative stress caused by dental resin monomers

S Krifka, G Spagnuolo, G Schmalz, H Schweikl - Biomaterials, 2013 - Elsevier
Dental composite resins are biomaterials commonly used to aesthetically restore the
structure and function of teeth impaired by caries, erosion, or fracture. Residual monomers …

Activation of the Nrf2-regulated antioxidant cell response inhibits HEMA-induced oxidative stress and supports cell viability

M Gallorini, C Petzel, C Bolay, KA Hiller, A Cataldi… - Biomaterials, 2015 - Elsevier
Oxidative stress due to increased formation of reactive oxygen species (ROS) in target cells
of dental resin monomers like 2-hydroxyethyl methacrylate (HEMA) is a major mechanism …

Synthesis, characterization, and mechanistic studies of a gold nanoparticle–amphotericin B covalent conjugate with enhanced antileishmanial efficacy and reduced …

P Kumar, P Shivam, S Mandal, P Prasanna… - International Journal …, 2019 - Taylor & Francis
Background Amphotericin B (AmB) as a liposomal formulation of AmBisome is the first line of
treatment for the disease, visceral leishmaniasis, caused by the parasite Leishmania …

The effect of selected dental materials used in conservative dentistry, endodontics, surgery, and orthodontics as well as during the periodontal treatment on the redox …

I Zieniewska, M Maciejczyk, A Zalewska - International Journal of …, 2020 - mdpi.com
Oxidative stress (OS) is a redox homeostasis disorder that results in oxidation of cell
components and thus disturbs cell metabolism. OS is induced by numerous internal as well …

The influence of glutathione on redox regulation by antioxidant proteins and apoptosis in macrophages exposed to 2-hydroxyethyl methacrylate (HEMA)

S Krifka, KA Hiller, G Spagnuolo, A Jewett, G Schmalz… - Biomaterials, 2012 - Elsevier
Resin monomers like 2-hydroxyethyl methacrylate (HEMA) disturb cell functions including
responses of the innate immune system, mineralization and differentiation, or induce cell …

HEMA‐induced cytotoxicity: oxidative stress, genotoxicity and apoptosis

M Gallorini, A Cataldi… - International endodontic …, 2014 - Wiley Online Library
Dental resin composites consist of organic polymers with inorganic fillers used as bonding
resins and direct filling materials in dentine adhesives and as sealing agents for inlays …

Dental resin monomers induce early and potent oxidative damage on human odontoblast-like cells

PA Baldion, ML Velandia-Romero… - Chemico-Biological …, 2021 - Elsevier
Resin-based dental materials consist of filler particles and different monomers that are light
cured in situ to re-establish dental function and aesthetics. Due to the degree of conversion …

In vitro evaluation of dental resin monomers, triethylene glycol dimethacrylate (Tegdma), and 2-Hydroxyethyl methacrylate (Hema) in primary human melanocytes: a …

S Goenka - Oral, 2023 - mdpi.com
Triethylene glycol dimethacrylate (TEGDMA) and 2-hydroxyethyl methacrylate (HEMA), two
resin monomers often used in dental restorative materials, are leached due to insufficient …

Cell toxicity of methacrylate monomers—The role of glutathione adduct formation

V Ansteinsson, HB Kopperud… - … Research Part A: An …, 2013 - Wiley Online Library
Polymer‐based dental restorative materials are designed to polymerize in situ. However, the
conversion of methacrylate monomer to polymer is never complete, and leakage of the …