Targeting the tumor stroma for cancer therapy

M Xu, T Zhang, R Xia, Y Wei, X Wei - Molecular Cancer, 2022 - Springer
Tumors are comprised of both cancer cells and surrounding stromal components. As an
essential part of the tumor microenvironment, the tumor stroma is highly dynamic …

The role of tumor microenvironment in cancer metastasis: Molecular mechanisms and therapeutic opportunities

CM Neophytou, M Panagi, T Stylianopoulos… - Cancers, 2021 - mdpi.com
Simple Summary Metastasis, the process by which cancer cells escape primary tumor site
and colonize distant organs, is responsible for most cancer-related deaths. The tumor …

Exosomes: another intercellular lipometabolic communication mediators in digestive system neoplasms?

S Li, R Dong, Z Kang, H Li, X Wu, T Li - Cytokine & growth factor reviews, 2023 - Elsevier
Neoplasms are one of the most concerned public health problems worldwide. Digestive
system neoplasms, with a high morbidity and mortality, is one of the most common malignant …

[HTML][HTML] Translational insights into stem cell preconditioning: from molecular mechanisms to preclinical applications

K Moeinabadi-Bidgoli, A Babajani… - Biomedicine & …, 2021 - Elsevier
Cell-based therapy (CBT) is a revolutionary approach for curing a variety of degenerative
diseases. Stem cell-based regenerative medicine is a novel strategy for treating tissue …

Exosomes and cancer: from molecular mechanisms to clinical applications

A Jafari, A Babajani, M Abdollahpour-Alitappeh… - Medical Oncology, 2021 - Springer
Exosomes are extracellular nanovesicles secreted from almost all types of normal and
cancer cells. Collective evidence suggests that exosomes participate in cell–cell …

Mesenchymal stem cell: a friend or foe in anti-tumor immunity

CR Harrell, A Volarevic, VG Djonov, N Jovicic… - International Journal of …, 2021 - mdpi.com
Mesenchymal stem cells (MSCs) are self-renewable, multipotent stem cells that regulate the
phenotype and function of all immune cells that participate in anti-tumor immunity. MSCs …

The cross-talks among bone morphogenetic protein (BMP) signaling and other prominent pathways involved in neural differentiation

A Manzari-Tavakoli, A Babajani, MH Farjoo… - Frontiers in Molecular …, 2022 - frontiersin.org
The bone morphogenetic proteins (BMPs) are a group of potent morphogens which are
critical for the patterning, development, and function of the central nervous system. The …

[HTML][HTML] Current progress of mesenchymal stem cell membrane-camouflaged nanoparticles for targeted therapy

L Fan, A Wei, Z Gao, X Mu - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Nanodrug delivery systems have been widely used in disease treatment. However, weak
drug targeting, easy to be cleared by the immune system, and low biocompatibility are great …

Enhancement strategies for mesenchymal stem cells and related therapies

S Alagesan, J Brady, D Byrnes, J Fandiño… - Stem Cell Research & …, 2022 - Springer
Cell therapy, particularly mesenchymal stem/stromal (MSC) therapy, has been investigated
for a wide variety of disease indications, particularly those with inflammatory pathologies …

Phytomediated selenium nanoparticles and light regimes elicited in vitro callus cultures for biomass accumulation and secondary metabolite production in Caralluma …

A Ali, ZR Mashwani, NI Raja, S Mohammad… - Frontiers in Plant …, 2023 - frontiersin.org
Introduction Caralluma tuberculata holds significant importance as a medicinal plant due to
its abundance of bioactive metabolites, which offer a wide range of therapeutic potentials …