The Nrf2/HO‐1 Axis as targets for flavanones: Neuroprotection by pinocembrin, naringenin, and Eriodictyol
S Habtemariam - Oxidative medicine and cellular longevity, 2019 - Wiley Online Library
Flavanones are a group of flavonoids that derive from their immediate chalcone precursors
through the action of chalcone isomerase enzymes. The Aromatic A and B rings, C4‐keto …
through the action of chalcone isomerase enzymes. The Aromatic A and B rings, C4‐keto …
On the neuroprotective effects of naringenin: pharmacological targets, signaling pathways, molecular mechanisms, and clinical perspective
As a group of progressive, chronic, and disabling disorders, neurodegenerative diseases
(NDs) affect millions of people worldwide, and are on the rise. NDs are known as the …
(NDs) affect millions of people worldwide, and are on the rise. NDs are known as the …
Citrus reticulata Blanco (the common mandarin) fruit: An updated review of its bioactive, extraction types, food quality, therapeutic merits, and bio-waste valorization …
Fruits are regarded as the richest dietary sources of polyphenols, carotenoids, terpenoids,
and limonoids, making them highly desired prospects for the functional food industry. Citrus …
and limonoids, making them highly desired prospects for the functional food industry. Citrus …
Therapeutic potential of naringin in neurological disorders
Neurological illnesses are multifactorial incurable debilitating disorders that may cause
neurodegeneration. These diseases influence approximately 30 million people around the …
neurodegeneration. These diseases influence approximately 30 million people around the …
PERK pathway and neurodegenerative disease: to inhibit or to activate?
T Shacham, C Patel, GZ Lederkremer - Biomolecules, 2021 - mdpi.com
With the extension of life span in recent decades, there is an increasing burden of late-onset
neurodegenerative diseases, for which effective treatments are lacking. Neurodegenerative …
neurodegenerative diseases, for which effective treatments are lacking. Neurodegenerative …
Dysregulation of CRMP2 post-translational modifications drive its pathological functions
A Moutal, KA White, A Chefdeville, RN Laufmann… - Molecular …, 2019 - Springer
Collapsin response mediator proteins (CRMPs) are a family of ubiquitously expressed,
homologous phosphoproteins best known for coordinating cytoskeletal formation and …
homologous phosphoproteins best known for coordinating cytoskeletal formation and …
Effects and underlying mechanisms of bioactive compounds on type 2 diabetes mellitus and Alzheimer's disease
Type 2 diabetes mellitus is a complicated metabolic disorder characterized by
hyperglycemia and glucose intolerance. Alzheimer's disease is a progressive brain disorder …
hyperglycemia and glucose intolerance. Alzheimer's disease is a progressive brain disorder …
[HTML][HTML] Evaluation of terpenes rich Hura crepitans extract on glucose regulation and diabetic complications in STZ-induced diabetic rats
The continual increase in global diabetic statistics portends decreased productivity and life
spans, thus making it a disease of concern requiring more effective and safe therapeutic …
spans, thus making it a disease of concern requiring more effective and safe therapeutic …
Paradigms and success stories of natural products in drug discovery against neurodegenerative disorders (NDDs)
Neurodegenerative disorders (NDDs) are multifaceted complex disorders that have put a
great health and economic burden around the globe nowadays. The multi-factorial nature of …
great health and economic burden around the globe nowadays. The multi-factorial nature of …
Recent applications of bioinformatics in target identification and drug discovery for Alzheimer's disease
Alzheimer's disease (AD) is a complex multifactorial neurodegenerative disease
characterized by progressive memory loss. The main pathological features of the disease …
characterized by progressive memory loss. The main pathological features of the disease …