Retinal development is under the coordinated control of overlapping networks of signaling
pathways and transcription factors. The paper was conceived as a review of the data and …

The p2 progenitor domain in the ventral spinal cord gives rise to two interneuron subtypes:
V2a and V2b. Delta-Notch-mediated cell-cell interactions between postmitotic immature …

MicroRNAs (miRNAs) are involved in crucial steps of neurogenesis, neural differentiation,
and neuronal plasticity. Here we review experimental evidence suggesting that miRNAs …

Cell identity is acquired in different brain structures according to a stereotyped timing
schedule, by accommodating the proliferation of multipotent progenitor cells and the …

Progenitor cells in the central nervous system must leave the cell cycle to become neurons
and glia, but the signals that coordinate this transition remain largely unknown. We …

The vertebrate spinal cord contains distinct classes of cells that form at precise dorsal–
ventral locations and express specific combinations of transcription factors. In amniotes, V2 …

Long non-coding RNAs (lncRNAs) are RNA molecules with a transcript length of> 200 nt
which do not encode proteins, however, they have important functions in the form of RNA at …

Background In recent years, considerable knowledge has been gained on the molecular
mechanisms underlying retinal cell fate specification. However, hitherto studies focused …

The histone methyltransferase complex PRC2 controls key steps in developmental
transitions and cell fate choices; however, its roles in vertebrate eye development remain …

Chx10/Vsx2 and Vsx1 are the only Paired-like CVC (Prd-L: CVC) homeobox genes in the
mouse genome. Both are expressed in the retina and have important but distinct roles in …