Osteoarthritis (OA) is a major cause of disability and socioeconomic loss worldwide.
However, the current pharmacological approaches used to treat OA are largely palliative …

Decellularization of natural tissues to produce extracellular matrix is a promising method for
three-dimensional scaffolding and for understanding microenvironment of the tissue of …

Decellularized materials (DMs) are attracting more and more attention because of their
native structures, comparatively high bioactivity, low immunogenicity and good …

In view of their low immunogenicity, biomimetic internal environment, tissue-and organ-like
physicochemical properties, and functionalization potential, decellularized extracellular …

Cartilage, especially articular cartilage, is a unique connective tissue consisting of
chondrocytes and cartilage matrix that covers the surface of joints. It plays a critical role in …

Seriously compromised function of some organs can only be restored by transplantation.
Due to the shortage of human donors, the need to find another source of organs is of primary …

Advancements in the field of tissue engineering have led to the elucidation of physical and
chemical characteristics of physiological basement membranes (BM) as specialized forms of …

Articular cartilage (AC) has limited capacity for repair. The first attempt to repair cartilage
using tissue engineering was reported in 1977. Since then, cell-based interventions have …

Articular cartilage has very poor intrinsic healing ability and its repair remains a significant
clinical challenge. To promote neocartilage regeneration, we fabricated two collagen (Col) …

Injury of articular cartilage can cause osteoarthritis and seriously affect the physical and
mental health of patients. Unfortunately, current surgical treatment techniques that are …