Accumulating data highlight the contribution of brain mitochondria and bioenergetics to
psychiatric disorders and stress-related pathologies. Although anxiety has not received …

Aging is associated with complex biological changes that can be accelerated, slowed, or
even temporarily reversed by biological and non-biological factors. This article focuses on …

In seeking to understand mental health and disease, it is fundamental to identify the
biological substrates that draw together the experiences and physiological processes that …

Mitochondria, the 'powerhouse'of eukaryotic cells, play a key role in cellular homeostasis.
However, defective mitochondria increase mitochondrial ROS (mtROS) production and cell …

Increases in depressive and suicide-related symptoms among United States adolescents
have been recently linked to increased use of smartphones. Understanding of the brain …

Objective To investigate plasma levels of circulating cell-free mitochondrial DNA (ccf-
mtDNA) in patients with social anxiety disorder (SAD) and healthy controls (HC). Methods In …

Mitochondrial dysfunction is implicated in the pathophysiology of major depressive disorder
(MDD). This dysfunction can be indirectly assessed using the mitochondrial DNA (mtDNA) …

Major depressive disorder (MDD) is one of the most prevalent stress-related mental
disorders worldwide. Several biological mechanisms underlying the pathophysiology of …

Exposure to polycyclic aromatic hydrocarbons (PAHs) during pregnancy is a risk factor for
adverse neurobehavioral development outcomes. Mitochondrial DNA are sensitive to …

We define and discuss several proposed biological aging markers that have been examined
in SMDs, we review the most recent findings, and we conclude with opinions regarding the …