Fibrosis is a process characterized by an excessive accumulation of the extracellular matrix
as a response to different types of tissue injuries, which leads to organ dysfunction. The …

The key players of the chronic kidney disease-mineral and bone disorders (CKD-MBD) are
calcium, phosphate, PTH, FGF23, and the vitamin D hormonal system. The progressive …

Background Abnormalities in serum phosphorus, calcium and parathyroid hormone (PTH)
have been associated with poor survival in haemodialysis patients. This COSMOS (Current …

Hyperphosphatemia has been associated with higher mortality risk in CKD 5 patients
receiving dialysis. Here, we determined the association between the use of single and …

Background and aims In elderly subjects, renal insufficiency and osteoporosis often coexist
with high risk of fracture and elevated socio-economic burden. Today a large number of …

Background Benefits of phosphate-lowering interventions on clinical outcomes in patients
with CKD are unclear; systematic reviews have predominantly involved patients on dialysis …

Management of hyperphosphatemia in patients with dialysis-dependent chronic kidney
disease remains a major challenge, requiring a multifaceted approach that includes dietary …

Background Bone fragility fractures are associated with high morbidity and mortality. This
study analysed the association between the current biochemical parameters of chronic …

ABSTRACT Background Due to the Russian–Ukrainian war, some of the about 10 000
adults requiring dialysis in Ukraine fled their country to continue dialysis abroad. To better …

Background End stage renal disease (ESRD) patients on renal replacement therapy (RRT)
with diabetes mellitus (DM) have a higher mortality rate and an increase prevalence of …