the epidemiologic burden of non‐alcoholic fatty liver disease across the world

L Henry, J Paik, ZM Younossi - Alimentary pharmacology & …, 2022 - Wiley Online Library
Background The prevalence of non‐alcoholic fatty liver disease (NAFLD) is increasing in
parallel with obesity and type 2 diabetes. Aim To review the global epidemiology of NAFLD …

Epidemiology, pathogenesis, diagnosis and emerging treatment of nonalcoholic fatty liver disease

E Makri, A Goulas, SA Polyzos - Archives of medical research, 2021 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease, with an
estimated rising prevalence, in concert with the epidemics of obesity and type 2 diabetes …

Lean NAFLD: a distinct entity shaped by differential metabolic adaptation

F Chen, S Esmaili, GB Rogers, E Bugianesi, S Petta… - Hepatology, 2020 - journals.lww.com
Conclusions This study demonstrates that E. multilocularis can induce T‐cell exhaustion
through inhibitory receptor TIGIT, and that blocking this checkpoint may reverse the …

Geographical similarity and differences in the burden and genetic predisposition of NAFLD

TCF Yip, E Vilar‐Gomez, S Petta, Y Yilmaz… - Hepatology, 2023 - journals.lww.com
NAFLD has become a major public health problem for more than 2 decades with a growing
prevalence in parallel with the epidemic of obesity and type 2 diabetes (T2D). The disease …

Accuracy of Fibrosis-4 index and non-alcoholic fatty liver disease fibrosis scores in metabolic (dysfunction) associated fatty liver disease according to body mass index …

F Eren, E Kaya, Y Yilmaz - European journal of gastroenterology & …, 2022 - journals.lww.com
Methods A total of 560 patients (28 lean, 174 overweight, 229 obese, 89 severely obese, 40
morbidly obese) were included. Diagnostic performances and optimal cut-off values for FIB …

Role of intensive dietary and lifestyle interventions in the treatment of lean nonalcoholic fatty liver disease patients

PH Varol, E Kaya, E Alphan… - European journal of …, 2020 - journals.lww.com
Methods In total, 35 patients (14 lean and 21 obese) were included in the study. All patients
underwent transient elastography examinations, and controlled attenuation parameter …

[HTML][HTML] Non-alcoholic fatty liver disease: A growing public health problem in Turkey

E Kaya, Y Yılmaz - The Turkish Journal of Gastroenterology, 2019 - ncbi.nlm.nih.gov
Non-alcoholic fatty liver disease (NAFLD) is histologically classified as either non-alcoholic
fatty liver or non-alcoholic steatohepatitis (NASH). NASH is the progressive subtype of …

Fatty liver through the ages: nonalcoholic steatohepatitis

ZM Younossi, L Henry - Endocrine Practice, 2022 - Elsevier
Objective The global epidemic of obesity and type 2 diabetes mellitus is the main driver of
the growing global prevalence of nonalcoholic fatty liver disease (NAFLD). We aimed to …

[HTML][HTML] Metabolic-associated Fatty Liver Disease: Time to integrate ground-breaking new terminology to our clinical practice?

CO Demirtas, Y Yilmaz - Hepatology Forum, 2020 - ncbi.nlm.nih.gov
To address these issues, an international expert panel consensus was recently reached by
32 distinguished experts from 22 countries to propose a more comprehensive redefinition of …

[HTML][HTML] The utility of noninvasive scores in non-alcoholic fatty liver disease patients with normal and elevated serum transaminases

E Kaya, A Bakir, F Eren, Y Yilmaz - Hepatology Forum, 2020 - ncbi.nlm.nih.gov
Results FIB-4 cutoffs of< 1.3 and< 1.45 for low risk of advanced fibrosis had a sensitivity of
70% and 54% in patients with elevated transaminases and 70% and 52% in patients with …