Ketamine and serotonergic psychedelics: an update on the mechanisms and biosignatures underlying rapid-acting antidepressant treatment
The discovery of ketamine as a rapid-acting antidepressant spurred significant research to
understand its underlying mechanisms of action and to identify other novel compounds that …
understand its underlying mechanisms of action and to identify other novel compounds that …
[HTML][HTML] More than meets the eye: The role of sensory dimensions in psychedelic brain dynamics, experience, and therapeutics
Psychedelics are undergoing a major resurgence of scientific and clinical interest. While
multiple theories and frameworks have been proposed, there is yet no universal agreement …
multiple theories and frameworks have been proposed, there is yet no universal agreement …
Comparison of psychedelic and near-death or other non-ordinary experiences in changing attitudes about death and dying
Both psychedelic drug experiences and near-death experiences can occasion changes in
perspectives on death and dying, but there have been few direct comparisons of these …
perspectives on death and dying, but there have been few direct comparisons of these …
Trips and neurotransmitters: Discovering principled patterns across 6850 hallucinogenic experiences
Psychedelics probably alter states of consciousness by disrupting how the higher
association cortex governs bottom-up sensory signals. Individual hallucinogenic drugs are …
association cortex governs bottom-up sensory signals. Individual hallucinogenic drugs are …
Psilocybin analog 4-OH-DiPT enhances fear extinction and GABAergic inhibition of principal neurons in the basolateral amygdala
Psychedelics such as psilocybin show great promise for the treatment of depression and
PTSD, but their long duration of action poses practical limitations for patient access. 4-OH …
PTSD, but their long duration of action poses practical limitations for patient access. 4-OH …
Neural and subjective effects of inhaled N, N-dimethyltryptamine in natural settings
Background: N, N-dimethyltryptamine is a short-acting psychedelic tryptamine found
naturally in many plants and animals. Few studies to date have addressed the neural and …
naturally in many plants and animals. Few studies to date have addressed the neural and …
Synergistic, multi-level understanding of psychedelics: three systematic reviews and meta-analyses of their pharmacology, neuroimaging and phenomenology
K Shinozuka, K Jerotic, P Mediano, AT Zhao… - Translational …, 2024 - nature.com
Serotonergic psychedelics induce altered states of consciousness and have shown potential
for treating a variety of neuropsychiatric disorders, including depression and addiction. Yet …
for treating a variety of neuropsychiatric disorders, including depression and addiction. Yet …
Analysis of recreational psychedelic substance use experiences classified by substance
A Hase, M Erdmann, V Limbach, G Hasler - Psychopharmacology, 2022 - Springer
Rationale and objectives Differences among psychedelic substances regarding their
subjective experiences are clinically and scientifically interesting. Quantitative linguistic …
subjective experiences are clinically and scientifically interesting. Quantitative linguistic …
Bedside to bench: the outlook for psychedelic research
VP Acero, ES Cribas, KD Browne, O Rivellini… - Frontiers in …, 2023 - frontiersin.org
There has recently been a resurgence of interest in psychedelic compounds based on
studies demonstrating their potential therapeutic applications in treating post-traumatic …
studies demonstrating their potential therapeutic applications in treating post-traumatic …
Molecular and functional imaging studies of psychedelic drug action in animals and humans
Hallucinogens are a loosely defined group of compounds including LSD, N, N-
dimethyltryptamines, mescaline, psilocybin/psilocin, and 2, 5-dimethoxy-4 …
dimethyltryptamines, mescaline, psilocybin/psilocin, and 2, 5-dimethoxy-4 …