Mesolimbic dopaminergic pathways in fear conditioning

MA Pezze, J Feldon - Progress in neurobiology, 2004 - Elsevier
One of the most common paradigms used to study the biological basis of emotion, as well as
of learning and memory, is Pavlovian fear conditioning. In the acquisition phase of a fear …

Do novel antipsychotics have similar pharmacological characteristics? A review of the evidence

J Arnt, T Skarsfeldt - Neuropsychopharmacology, 1998 - nature.com
The pharmacological properties of the novel antipsychotic drugs (APDs) risperidone,
sertindole, olanzapine, quetiapine, ziprasidone, remoxipride, and amperozide are reviewed …

Pharmacology and behavioral pharmacology of the mesocortical dopamine system

TM Tzschentke - Progress in neurobiology, 2001 - Elsevier
The prefrontal cortex (PFC) has long been known to be involved in the mediation of complex
behavioral responses. Considerable research efforts are directed towards refining the …

The" two-headed" latent inhibition model of schizophrenia: modeling positive and negative symptoms and their treatment

I Weiner - Psychopharmacology, 2003 - Springer
Rationale Latent inhibition (LI), namely, poorer performance on a learning task involving a
previously pre-exposed non-reinforced stimulus, is disrupted in the rat by the dopamine (DA) …

Serotonin receptors in cognitive behaviors

MC Buhot - Current opinion in neurobiology, 1997 - Elsevier
The serotonergic system appears to play a role in behaviors that involve a high cognitive
demand and in memory improvement or recovery from impaired cognitive performance, as …

Addiction, personality and motivation

HJ Eysenck - Human Psychopharmacology: Clinical and …, 1997 - Wiley Online Library
It is suggested that addictive behaviour, so called, fits into a psychological resource model.
In other words, the habits in question are acquired because they serve a useful function for …

The amphetamine-induced sensitized state as a model of schizophrenia

RE Featherstone, S Kapur, PJ Fletcher - Progress in Neuro …, 2007 - Elsevier
Schizophrenia is a serious psychiatric disorder which impacts a broad range of cognitive,
behavioural and emotional domains. In animals, exposure to an intermittent, escalating dose …

Integrating schizophrenia

JA Gray - Schizophrenia bulletin, 1998 - academic.oup.com
A neuropsychological theory of the positive symptoms of schizophrenia proposed by JA
Gray et al. is reviewed in light of subsequent evidence from studies of latent inhibition in …

The role of serotonergic-cholinergic interactions in the mediation of cognitive behaviour

T Steckler, A Sahgal - Behavioural brain research, 1995 - Elsevier
Cholinergic systems have been linked to cognitive processes such as attention, learning
and mnemonic function. However, other neurotransmitter systems, such as the serotonergic …

Ondansetron: a review of its pharmacology and preliminary clinical findings in novel applications

MI Wilde, A Markham - Drugs, 1996 - Springer
Synopsis The use of ondansetron, a selective serotonin 5-HT 3 receptor antagonist, is well
established in patients with nausea and vomiting associated with cancer chemotherapy …