[HTML][HTML] Chlorogenic acid: Potential source of natural drugs for the therapeutics of fibrosis and cancer

EO Nwafor, P Lu, Y Zhang, R Liu, H Peng, B Xing… - Translational …, 2022 - Elsevier
Fibrosis and cancer is described by some epidemiological studies as chronic stages of
different disease conditions typically characterized by uncontrolled accumulation of extra …

The impact of coffee and its selected bioactive compounds on the development and progression of colorectal cancer in vivo and in vitro

RJ Bułdak, T Hejmo, M Osowski, Ł Bułdak, M Kukla… - Molecules, 2018 - mdpi.com
Coffee is one of the most popular beverages worldwide. Coffee contains bioactive
compounds that affect the human body such as caffeine, caffeic acid, chlorogenic acids …

Carvacrol inhibits proliferation and induces apoptosis in human colon cancer cells

K Fan, X Li, Y Cao, H Qi, L Li, Q Zhang, H Sun - Anti-cancer drugs, 2015 - journals.lww.com
Colon cancer is one of the most common malignancies worldwide and has a high mortality
rate. Carvacrol is a major component of oregano and thyme essential oils and shows …

Chlorogenic acid induces reactive oxygen species generation and inhibits the viability of human colon cancer cells

N Hou, N Liu, J Han, Y Yan, J Li - Anti-cancer drugs, 2017 - journals.lww.com
Chlorogenic acid (CGA) is one of the polyphenols identified in the human diet. Previous
studies have shown that CGA plays a protective role against liver diseases. The colon plays …

Cytotoxic and apoptogenic effect of hypericin, the bioactive component of Hypericum perforatum on the MCF-7 human breast cancer cell line

SA Mirmalek, MA Azizi, E Jangholi… - Cancer cell …, 2015 - Springer
Background Breast cancer is the most prevalent malignancies among the women that have
a high mortality. Previous studies demonstrated that hypericin, a bioactive component of …

Polar Constituents and Biological Activity of the Berry-Like Fruits from Hypericum androsaemum L.

G Caprioli, A Alunno, D Beghelli, A Bianco… - Frontiers in plant …, 2016 - frontiersin.org
Hypericum androsaemum, also known as Tutsan, is a small evergreen shrub common in the
Mediterranean basin where it is traditionally used as diuretic and hepatoprotective herbal …

New potential pharmaceutical applications of hypericum species

M Marrelli, G Statti, F Conforti… - Mini reviews in …, 2016 - ingentaconnect.com
The genus Hypericum includes more than 450 species distributed in Europe, North America,
North Africa and West Asia. These plants are widely used in folk medicine for the treatment …

[HTML][HTML] Integration of in vitro and in silico perspectives to explain chemical characterization, biological potential and anticancer effects of Hypericum salsugineum: A …

O Bender, EJ Llorent-Martínez, G Zengin, A Mollica… - PLoS …, 2018 - journals.plos.org
The genus Hypericum is one of the most popular genera in both traditional medicine and
scientific platform. This study is designed to provide conceptual insights on the biological …

Synthesis of 6, 8-diaminopurines via acid-induced cascade cyclization of 5-aminoimidazole precursors and preliminary anticancer evaluation

NR Senhorães, BF Silva, R Sousa, BP Leite… - Organic & …, 2024 - pubs.rsc.org
Inspired by the pharmacological interest generated by 6-substituted purine roscovitine for
cancer treatment, 5-aminoimidazole-4-carboxamidine precursors containing a cyanamide …

Ontogenetic changes in phenolic contents and volatile composition of Hypericum androsaemum and Hypericum xylosteifolium

C Cirak, F Seyis, A Özcan, E Yurteri - Biochemical Systematics and …, 2022 - Elsevier
We described the ontogenetic changes in phenolic contents and volatile composition of
Hypericum androsaemum L. and Hypericum xylosteifolium (Spach) N. Robson from Turkish …