The benefits and mechanisms of exercise training for Parkinson's disease

YS Feng, SD Yang, ZX Tan, MM Wang, Y Xing, F Dong… - Life sciences, 2020 - Elsevier
Parkinson's disease (PD) is a significantly progressive neurodegenerative disease
characterised by both motor and nonmotor disorders. The main pathological characteristics …

Effects of acute cardiovascular exercise on motor memory encoding and consolidation: A systematic review with meta-analysis

P Wanner, FH Cheng, S Steib - Neuroscience & Biobehavioral Reviews, 2020 - Elsevier
Emerging evidence indicates that acute bouts of cardiovascular exercise promote motor
memory formation. In this preregistered meta-analysis (CRD42018106288) we synthesize …

[HTML][HTML] Understanding the neurophysiological and molecular mechanisms of exercise-induced neuroplasticity in cortical and descending motor pathways: where do …

C Nicolini, M Fahnestock, MJ Gibala, AJ Nelson - Neuroscience, 2021 - Elsevier
Exercise is a promising, cost-effective intervention to augment successful aging and
neurorehabilitation. Decline of gray and white matter accompanies physiological aging and …

High-intensity acute exercise impacts motor learning in healthy older adults

EM Taylor, CJ Cadwallader, D Curtin… - npj Science of …, 2024 - nature.com
Healthy aging is associated with changes in motor sequence learning, with some studies
indicating decline in motor skill learning in older age. Acute cardiorespiratory exercise has …

Apelin-13 protects dopaminergic neurons in MPTP-induced Parkinson's disease model mice through inhibiting endoplasmic reticulum stress and promoting …

J Zhu, S Dou, Y Jiang, J Chen, C Wang, B Cheng - Brain Research, 2019 - Elsevier
The dopaminergic neurodegeneration in the substantia nigra pars compacta (SNpc) and
striatum of the midbrain is the important pathological feature of Parkinson's disease (PD). It …

[HTML][HTML] Exercise, Neuroprotective Exerkines, and Parkinson's Disease: A Narrative Review

AK Mitchell, RR Bliss, FC Church - Biomolecules, 2024 - pmc.ncbi.nlm.nih.gov
Parkinson's disease (PD) is a prevalent neurodegenerative disease in which treatment often
includes an exercise regimen. Exercise is neuroprotective in animal models of PD, and …

Parkinson's disease patients benefit from bicycling-a systematic review and meta-analysis

M Tiihonen, BU Westner, M Butz, SS Dalal - NPJ Parkinson's disease, 2021 - nature.com
Many Parkinson's disease (PD) patients are able to ride a bicycle despite being severely
compromised by gait disturbances up to freezing of gait. This review [PROSPERO CRD …

Exercise-boosted mitochondrial remodeling in Parkinson's disease

JC Magaña, CM Deus, M Giné-Garriga, J Montané… - Biomedicines, 2022 - mdpi.com
Parkinson's disease (PD) is a movement disorder characterized by the progressive
degeneration of dopaminergic neurons resulting in dopamine deficiency in the striatum …

Influences of aerobic exercise on motor sequence learning and corticomotor excitability in people with Parkinson's disease

ST Chan, CH Tai, LY Wang, JJ Luh… - … and Neural Repair, 2023 - journals.sagepub.com
Background People with Parkinson's disease (PD) are known to have motor learning
difficulties. Although numerous studies have demonstrated that a single bout of aerobic …

Short-Term Effects of Single-Session Split-Belt Treadmill Training on Dual-Task Performance in Parkinson's Disease and Healthy Elderly

N D'Cruz, J Seuthe, P Ginis, F Hulzinga… - Frontiers in …, 2020 - frontiersin.org
Background: Dual-tasking is challenging for people with Parkinson's disease and freezing of
gait (PD+ FOG) and can exacerbate freezing episodes and falls. Split-belt treadmill training …