Osteoarthritis (OA) is a degenerative joint disease characterized by low-grade inflammation
and high levels of clinical heterogeneity. Aberrant chondrocyte metabolism is a response to …

Osteoarthritis (OA) is an age-related cartilage degenerative disease, and chondrocyte
senescence has been extensively studied in recent years. Increased numbers of senescent …

Osteoarthritis (OA) is a common chronic disease and a significant health concern that needs
to be urgently solved. OA affects the cartilage and entire joint tissues, including the …

We conducted a systematic review of the literature on the effects of cordycepin on cell
survival and proliferation, inflammation, signal transduction and animal models. A total of …

summary Great progress continues to be made in our understanding of the multiple facets of
osteoarthritis (OA) biology. Here, we review the major advances in this field and progress …

Background Physical inactivity is an independent risk factor for type 2 diabetes (T2D).
Osteoarthritis (OA) is a common joint disease that limits patients' physical activity, which may …

Osteoarthritis (OA) is a highly prevalent joint disease that is associated with pain, loss of
function, and high direct and indirect economic costs. The current therapeutic options are …

Objectives An association between osteoarthritis (OA) and atherosclerosis (AT) has been
proposed, but evidence is controverted, with recent meta-analysis showing disparate results …

Metformin is an oral antihyperglycemic drug widely used to treat type 2 diabetes, acting via
indirect activation of 5′ Adenosine Monophosphate-activated Protein Kinase (AMPK) …

Abstract Objective The association between Metabolic Syndrome (MetS), its components,
and the risk of osteoarthritis (OA) has been a topic of conflicting evidence in different studies …