Convection-enhanced delivery (CED) is a bulk flow–driven process. Its properties permit
direct, homogeneous, targeted perfusion of CNS regions with putative therapeutics while …

Convection-enhanced delivery (CED) is a method used to increase transport of therapeutics
in and around brain tumors. CED works through locally applying a pressure differential to …

Background Convection enhanced delivery (CED) infuses drugs directly into brain tissue.
Needle insertion is required and results in tissue damage which can promote flowback …

Convection-enhanced drug delivery is a technique where a therapeutic agent is infused
under positive pressure directly into the brain tissue. For predicting the final concentration …

Brain disorders represent an ever-increasing health challenge worldwide. While
conventional drug therapies are less effective due to the presence of the blood-brain barrier …

Validation assesses the accuracy of a mathematical model by comparing simulation results
to experimentally measured quantities of interest. Model validation experiments emphasize …

Targeted drug delivery in the brain is instrumental in the treatment of lethal brain diseases,
such as glioblastoma multiforme, the most aggressive primary central nervous system …

Although targeted magnetic hyperthermia has been proven to be an effective tumor ablation
technique, its use in clinical applications is still scarce particularly due to the difficulty in …

Convection-enhanced delivery (CED) is a promising local delivery technique for overcoming
the blood–brain barrier (BBB) and treating diseases of the central nervous system (CNS) …

Convection-enhanced delivery is a technique to bypass the blood–brain barrier and deliver
therapeutic drugs into the brain tissue. However, animal investigations and preliminary …