Brown and beige adipocytes are mitochondria-enriched cells capable of dissipating energy
in the form of heat. These thermogenic fat cells were originally considered to function solely …

Adipose tissues are dynamic tissues that play crucial physiological roles in maintaining
health and homeostasis. Although white adipose tissue and brown adipose tissue are …

White fat stores excess energy, whereas brown and beige fat are thermogenic and dissipate
energy as heat. Thermogenic adipose tissues markedly improve glucose and lipid …

Adipose tissue is usually classified on the basis of its function as white, brown or beige
(brite). It is an important regulator of systemic metabolism, as shown by the fact that …

Antibodies are key immune effectors that confer protection against pathogenic threats. The
nature and longevity of the antibody response to SARS-CoV-2 infection are not well defined …

Cholesterol is an essential lipid and its synthesis is nutritionally and energetically costly,. In
mammals, cholesterol biosynthesis increases after feeding and is inhibited under fasting …

Thermogenic adipocytes possess a therapeutically appealing, energy-expending capacity,
which is canonically cold-induced by ligand-dependent activation of β-adrenergic G protein …

The Hippo-Yes-associated protein (YAP) signaling network plays a central role as an
integrator of signals that control cellular proliferation and differentiation. The past several …

The link between branched-chain amino acids (BCAAs) and obesity has been known for
decades but the functional role of BCAA metabolism in white adipose tissue (WAT) of obese …

Adipose tissue can recruit catabolic adipocytes that utilize chemical energy to dissipate heat.
This process occurs either by uncoupled respiration through uncoupling protein 1 (UCP1) or …