[HTML][HTML] Cancer immunotherapy: Pros, cons and beyond
S Tan, D Li, X Zhu - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Cancer immunotherapy is an innovative treatment for tumors today. In various experiments
and clinical studies, it has been found that immunotherapy does have incomparable …
and clinical studies, it has been found that immunotherapy does have incomparable …
Exhaustion and senescence: two crucial dysfunctional states of T cells in the tumor microenvironment
Y Zhao, Q Shao, G Peng - Cellular & molecular immunology, 2020 - nature.com
The failure of a massive influx of tumor-infiltrating T lymphocytes to eradicate tumor cells in
the tumor microenvironment is mainly due to the dysfunction of T cells hyporesponsive to …
the tumor microenvironment is mainly due to the dysfunction of T cells hyporesponsive to …
The molecular landscape of T cell exhaustion in the tumor microenvironment and reinvigoration strategies
M Heidari-Foroozan, A Rezalotfi… - International Reviews of …, 2024 - Taylor & Francis
Immunotherapy has emerged as a promising therapeutic approach for cancer treatment by
harnessing the immune system to target cancer cells. However, the efficacy of …
harnessing the immune system to target cancer cells. However, the efficacy of …
LAG-3 contribution to T cell downmodulation during acute respiratory viral infections
L Rodríguez-Guilarte, MA Ramírez, CA Andrade… - Viruses, 2023 - mdpi.com
LAG-3 is a type I transmembrane protein expressed on immune cells, such as activated T
cells, and binds to MHC class II with high affinity. LAG-3 is an inhibitory receptor, and its …
cells, and binds to MHC class II with high affinity. LAG-3 is an inhibitory receptor, and its …
Comprehensive analysis and validation reveal DEPDC1 as a potential diagnostic biomarker associated with tumor immunity in non-small-cell lung cancer
M Lv, X Li, Z Yin, H Yang, B Zhou - Plos one, 2024 - journals.plos.org
Current evidence suggests that DEP domain containing 1 (DEPDC1) has an important effect
on non-small-cell lung cancer (NSCLC). However, the diagnostic value and the regulatory …
on non-small-cell lung cancer (NSCLC). However, the diagnostic value and the regulatory …
Identification of the novel biomarkers involved in the mitochondrial metabolism-related reactive oxygen species and their role in lung cancer T-cell exhaustion and …
S Wang, B Liu, F Li, Z Tang, X Gu, X Yuan - Heliyon, 2024 - cell.com
Purpose To study the role of mitochondrial metabolism and obtain novel biomarkers in
immunotherapy for non-small cell lung cancer (NSCLC). Methods We collected the 188 …
immunotherapy for non-small cell lung cancer (NSCLC). Methods We collected the 188 …
Screening of the shared pathogenic genes of ulcerative colitis and colorectal cancer by integrated bioinformatics analysis
X Shi, J Yu, C Lu, Q Luo, C Xu, J Li… - Journal of Cellular and …, 2024 - Wiley Online Library
Ulcerative colitis (UC) is one of the high‐risk pathogenic factors for colorectal cancer (CRC).
However, the shared gene and signalling mechanisms between UC and CRC remain …
However, the shared gene and signalling mechanisms between UC and CRC remain …
[PDF][PDF] 恶性实体肿瘤患者外周血T 细胞中PD-1, LAG-3, TIM-3 的表达情况
袁园， 陈继中， 朱亦林， 张盛， 韩兴华， 潘跃银 - 安徽医科大学学报, 2020 - aydxb.cn
摘要目的探究恶性实体肿瘤患者淋巴细胞亚群及CD4+ T 细胞, CD8+ T 细胞上免疫检查点分子
PD-1, LAG-3, TIM-3 的表达情况. 方法使用流式细胞术(FCM) 对30 例恶性实体肿瘤患者和15 …
PD-1, LAG-3, TIM-3 的表达情况. 方法使用流式细胞术(FCM) 对30 例恶性实体肿瘤患者和15 …
9 Nanomedicine for Cancer Therapy
AK Rengan - … of Nanomaterials in Biotechnology, Medicine and …, 2024 - books.google.com
Significant research progress has been made towards comprehending the functioning of
cancer biology in previous two decades. The World Health Organization (WHO) reported 8.2 …
cancer biology in previous two decades. The World Health Organization (WHO) reported 8.2 …
TOP2A Serves as a Prognostic Marker Associated with Immune Infiltration in Hepatocellular Carcinoma
Q Su, S Zhang, J Ran - 2022 - researchsquare.com
Background TOP2A is a key enzyme that controls the topological state of DNA during DNA
replication and transcription. We aim to explore the role of TOP2A in hepatocellular …
replication and transcription. We aim to explore the role of TOP2A in hepatocellular …