Neuronal circuits of fear extinction
Fear extinction is a form of inhibitory learning that allows for the adaptive control of
conditioned fear responses. Although fear extinction is an active learning process that …
conditioned fear responses. Although fear extinction is an active learning process that …
Substrains matter in phenotyping of C57BL/6 mice
K Mekada, A Yoshiki - Experimental animals, 2021 - jstage.jst.go.jp
The inbred mouse strain C57BL/6 has been widely used as a background strain for
spontaneous and induced mutations. Developed in the 1930s, the C57BL/6 strain diverged …
spontaneous and induced mutations. Developed in the 1930s, the C57BL/6 strain diverged …
Genetic differences among C57BL/6 substrains
K Mekada, K Abe, A Murakami, S Nakamura… - Experimental …, 2009 - jstage.jst.go.jp
The C57BL/6 mouse is the most well-known inbred mouse strain, and has been widely used
as a genetic background for congenic and mutant mice. A number of C57BL/6 substrains …
as a genetic background for congenic and mutant mice. A number of C57BL/6 substrains …
Agouti C57BL/6N embryonic stem cells for mouse genetic resources
SJ Pettitt, Q Liang, XY Rairdan, JL Moran, HM Prosser… - Nature …, 2009 - nature.com
We report the characterization of a highly germline competent C57BL/6N mouse embryonic
stem cell line, JM8. To simplify breeding schemes, the dominant agouti coat color gene was …
stem cell line, JM8. To simplify breeding schemes, the dominant agouti coat color gene was …
[HTML][HTML] Behavioral tests assessing neuropsychiatric phenotypes in adolescent mice reveal strain-and sex-specific effects
A Eltokhi, B Kurpiers, C Pitzer - Scientific reports, 2020 - nature.com
In humans, infancy and adolescence are associated with major changes in synaptic
functions and ongoing maturation of neural networks, which underlie the major behavioral …
functions and ongoing maturation of neural networks, which underlie the major behavioral …
Strain and gender differences in the behavior of mouse lines commonly used in transgenic studies
The present study was aimed at establishing behavioral differences between three inbred
mouse strains (129S2/SvHsd, C57BL/6JOlaHsd, FVB/NHsd) and two F1 hybrid lines derived …
mouse strains (129S2/SvHsd, C57BL/6JOlaHsd, FVB/NHsd) and two F1 hybrid lines derived …
The role of 5-HT1A receptors in learning and memory
SO Ögren, TM Eriksson, E Elvander-Tottie… - Behavioural brain …, 2008 - Elsevier
The ascending serotonin (5-HT) neurons innervate the cerebral cortex, hippocampus,
septum and amygdala, all representing brain regions associated with various domains of …
septum and amygdala, all representing brain regions associated with various domains of …
Long‐term individual housing in C57BL/6J and DBA/2 mice: assessment of behavioral consequences
The aim of the present study was to investigate the effects of individual housing on mouse
behavior. The male mice of the C57BL/6J and DBA/2 strains were separated at the age of 4 …
behavior. The male mice of the C57BL/6J and DBA/2 strains were separated at the age of 4 …
Behavioral phenotyping of mice in pharmacological and toxicological research
T Karl, R Pabst, S von Hörsten - Experimental and Toxicologic Pathology, 2003 - Elsevier
The evaluation of behavioral effects is an important component for the in vivo screening of
drugs or potentially toxic compounds in mice. Ideally, such screening should be composed …
drugs or potentially toxic compounds in mice. Ideally, such screening should be composed …
[HTML][HTML] Self-organizing feature maps identify proteins critical to learning in a mouse model of down syndrome
Down syndrome (DS) is a chromosomal abnormality (trisomy of human chromosome 21)
associated with intellectual disability and affecting approximately one in 1000 live births …
associated with intellectual disability and affecting approximately one in 1000 live births …