Despite the overwhelming success of vaccines in preventing infectious diseases, there
remain numerous globally devastating diseases without fully protective vaccines, particularly …

The efficient spread of malaria from infected humans to mosquitoes is a major challenge for
malaria elimination initiatives. Gametocytes are the only Plasmodium life stage infectious to …

Malaria transmission-blocking vaccines (TBVs) aim to elicit human antibodies that inhibit
sporogonic development of Plasmodium falciparum in mosquitoes, thereby preventing …

Malaria is a deadly disease responsible for between 550,000 and 627,000 deaths annually.
There is a pressing need to develop vaccines focused on malaria elimination. The complex …

Malaria is a vector-borne parasitic disease caused by the apicomplexan protozoan parasite
Plasmodium. Malaria is a significant health problem and the leading cause of …

Malaria and schistosomiasis are two major parasitic diseases that remain leading causes of
morbidity and mortality worldwide. Co-infections of these two parasites are common in the …

Malaria remains one of the biggest health problems in the world. While significant reductions
in malaria morbidity and mortality had been achieved from 2000 to 2015, the favorable trend …

The global spread of coronavirus disease 2019 caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infection has provoked an urgent need for …

Conventional vaccinations and immunotherapies have encountered major roadblocks in
preventing infectious diseases like HIV, influenza, and malaria. These challenges are due to …

Nanotechnologies are considered to be of growing importance to the vaccine field. Through
decoration of immunogens on multivalent nanoparticles, designed nanovaccines can elicit …