Phycocyanin from Arthrospira platensis as Potential Anti-Cancer Drug: Review of In Vitro and In Vivo Studies

S Braune, A Krüger-Genge, S Kammerer, F Jung… - Life, 2021 - mdpi.com
The application of cytostatic drugs or natural substances to inhibit cancer growth and
progression is an important and evolving subject of cancer research. There has been a …

Anakoinosis: correcting aberrant homeostasis of cancer tissue—going beyond apoptosis induction

D Heudobler, F Lüke, M Vogelhuber, S Klobuch… - Frontiers in …, 2019 - frontiersin.org
The current approach to systemic therapy for metastatic cancer is aimed predominantly at
inducing apoptosis of cancer cells by blocking tumor-promoting signaling pathways or by …

CDK1 and HSP90AA1 appear as the novel regulatory genes in non-small cell lung cancer: a bioinformatics approach

N Bhattacharyya, S Gupta, S Sharma, A Soni… - Journal of Personalized …, 2022 - mdpi.com
Lung cancer is one of the most invasive cancers affecting over a million of the population.
Non-small cell lung cancer (NSCLC) constitutes up to 85% of all lung cancer cases, and …

Network pharmacology and bioinformatics approach reveals the therapeutic mechanism of action of curcumin in Alzheimer disease

D Vijh, MA Imam, MMU Haque, S Das, A Islam… - Metabolic Brain …, 2023 - Springer
Curcumin is a natural anti-inflammatory and antioxidant substance which plays a major role
in reducing the amyloid plaques formation, which is the major cause of Alzheimer's disease …

[HTML][HTML] Kinless hubs are potential target genes in prostate cancer network

IR Mangangcha, MZ Malik, O Kucuk, S Ali, RKB Singh - Genomics, 2020 - Elsevier
Complex disease networks can be studied successfully using network theoretical approach
which helps in finding key disease genes and associated disease modules. We studied …

Network medicine in ovarian cancer: topological properties to drug discovery

K Chirom, MZ Malik, IR Mangangcha… - Briefings in …, 2022 - academic.oup.com
Network medicine provides network theoretical tools, methods and properties to study
underlying laws governing human interactome to identify disease states and disease …

Discovering driver nodes in chronic kidney disease-related networks using Trader as a newly developed algorithm

Y Masoudi-Sobhanzadeh, A Gholaminejad… - Computers in Biology …, 2022 - Elsevier
Thanks to the advances in the field of computational-based biology, a huge volume of
disease-related data has been generated so far. From the existing data, the disease-related …

Methodology of predicting novel key regulators in ovarian cancer network: a network theoretical approach

MZ Malik, K Chirom, S Ali, R Ishrat, P Somvanshi… - BMC cancer, 2019 - Springer
Background Identification of key regulator/s in ovarian cancer (OC) network is important for
potential drug target and prevention from this cancer. This study proposes a method to …

Identification of key regulators in prostate cancer from gene expression datasets of patients

IR Mangangcha, MZ Malik, Ö Küçük, S Ali… - Scientific reports, 2019 - nature.com
Identification of key regulators and regulatory pathways is an important step in the discovery
of genes involved in cancer. Here, we propose a method to identify key regulators in …

The Role of Phytonutrient Kaempferol in the Prevention of Gastrointestinal Cancers: Recent Trends and Future Perspectives

T Singh, D Sharma, R Sharma, HS Tuli, S Haque… - Cancers, 2024 - mdpi.com
Simple Summary Kaempferol (3, 5, 7-trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one), a
flavonoid, is richly found in fruits and vegetables. Kaempferol has been proven to reduce …