The role of matrix metalloproteinases in periodontal disease

V Checchi, T Maravic, P Bellini, L Generali… - International Journal of …, 2020 - mdpi.com
This review provides a detailed description of matrix metalloproteinases (MMPs), focusing
on those that are known to have critical roles in bone and periodontal disease. Periodontal …

Host‐derived diagnostic markers related to soft tissue destruction and bone degradation in periodontitis

N Buduneli, DF Kinane - Journal of clinical periodontology, 2011 - Wiley Online Library
Buduneli N, Kinane DF: Host‐derived diagnostic markers related to soft tissue destruction
and bone degradation in periodontitis. J Clin Periodontol 2011; 38 (Suppl. 11): 85–105. doi …

A review of the relationship between tooth loss, periodontal disease, and cancer

MS Meyer, K Joshipura, E Giovannucci… - Cancer causes & …, 2008 - Springer
Recent studies have investigated the association between periodontal disease, tooth loss,
and several systemic diseases including cancer, cardiovascular disease, and preterm birth …

Is there a relationship between periodontal disease and oral cancer? A systematic review of currently available evidence

F Javed, S Warnakulasuriya - Critical reviews in oncology/hematology, 2016 - Elsevier
Oral cancer (OC) is known to have a multi-factorial etiology; tobacco, alcohol and betel quid
being the major risk factors. Tooth loss and periodontal disease (PD) have been implicated …

Periodontal disease immunology:'double indemnity'in protecting the host

JL Ebersole, DR Dawson III, LA Morford… - Periodontology …, 2013 - Wiley Online Library
During the last two to three decades our understanding of the immunobiology of periodontal
disease has increased exponentially, both with respect to the microbial agents triggering the …

Cranberry proanthocyanidins inhibit MMP production and activity

VD La, AB Howell, D Grenier - Journal of dental research, 2009 - journals.sagepub.com
Matrix metalloproteinases (MMPs) produced by resident and inflammatory cells in response
to periodontopathogens play a major role in periodontal tissue destruction. Our aim was to …

Neutrophil proteolytic activation cascades: a possible mechanistic link between chronic periodontitis and coronary heart disease

H Alfakry, E Malle, CN Koyani, PJ Pussinen… - Innate …, 2016 - journals.sagepub.com
Cardiovascular diseases are chronic inflammatory diseases that affect a large segment of
society. Coronary heart disease (CHD), the most common cardiovascular disease …

Altered gene expression levels of matrix metalloproteinases and their inhibitors in periodontitis‐affected gingival tissue

T Kubota, M Itagaki, C Hoshino… - Journal of …, 2008 - Wiley Online Library
Background: The balance between the degradation and synthesis of extracellular matrix
determines periodontal attachment levels and alveolar bone matrix concentration in …

Diagnostic potential and future directions of matrix metalloproteinases as biomarkers in gingival crevicular fluid of oral and systemic diseases

F Zhang, E Liu, A Radaic, X Yu, S Yang, C Yu… - International Journal of …, 2021 - Elsevier
Gingival crevicular fluid (GCF) is a physiological fluid and an inflammatory serum exudate
derived from the gingival plexus of blood vessels and mixed with host tissues and …

Mucin 4 and matrix metalloproteinase 7 as novel salivary biomarkers for periodontitis

A Lundmark, G Johannsen, K Eriksson… - Journal of clinical …, 2017 - Wiley Online Library
Aim Periodontitis is a chronic inflammatory disease, characterized by irreversible destruction
of tooth‐supporting tissue including alveolar bone. We recently reported mucin 4 (MUC 4) …