The Physics of micro-and nano-manipulation: Fundamentals and applications

S Zhuang, X Lin, X Yu, Z Zhao, F Liu, S Boccaletti… - Physics Reports, 2024 - Elsevier
Since the emergent advent of miniaturized technologies in the last century, the past ninety
years have witnessed the extensive use of micro-and nano-manipulation methods, which …

Microinjection in biomedical applications: An effortless autonomous omnidirectional microinjection system

S Zhuang, D Lei, X Yu, M Tong, W Lin… - IEEE Industrial …, 2023 - ieeexplore.ieee.org
Thanks to the advancements in micro-and nanomechatronics techniques, the capability to
inject foreign materials into target locations inside biosamples has become increasingly …

Design of an automated robotic microinjection system for batch injection of zebrafish embryos and larvae

Z Guo, N Ai, W Ge, Q Xu - Microsystems & Nanoengineering, 2024 - nature.com
This paper presents the design of a vision-based automated robotic microinjection system
for batch injection of both zebrafish embryos and larvae. A novel visual recognition algorithm …

Design and development of a dexterous bilateral robotic microinjection system based on haptic feedback

K Feng, Q Xu, LM Tam - IEEE Transactions on Automation …, 2022 - ieeexplore.ieee.org
In this paper, a dexterous bilateral robotic system with haptic feedback is designed and
developed for microinjection of biological samples. For the first time, the robotic system has …

Deep learning-enhanced dual-module large-throughput microinjection system for adherent cells

F Pan, Y Jiao, S Chen, L Xing… - IEEE Transactions on …, 2022 - ieeexplore.ieee.org
Despite the rapid development in providing precise delivery of extraneous samples to the
vast majority of cells, robotic microinjection is still hindered by cumbersome operations and …

Quality and Quantity Control of Mitochondria Injection Into Single Cells With Robot-Aided Micro-Manipulation System

A Shakoor, M Xie, W Gao, MM Gulzar… - IEEE Transactions on …, 2023 - ieeexplore.ieee.org
Mitochondrial dysfunction plays a significant role in the development of fatal diseases such
as aging, cancer, and Alzheimer's. Transferring mitochondria to cells is a new and potential …

An improved automated zebrafish larva high-throughput imaging system

G Zhang, X Yu, G Huang, D Lei, M Tong - Computers in Biology and …, 2021 - Elsevier
As a typical multicellular model organism, the zebrafish has been increasingly used in
biological research. Despite the efforts to develop automated zebrafish larva imaging …

A Fractional Viscoelastic Mechanical Model for Speed Optimization of Robotic Cell Microinjection

S Kang, X Yang, Y Li, H Wu, T Li - IEEE/ASME Transactions on …, 2024 - ieeexplore.ieee.org
Robotic microinjection has been widely applied in the biomedical field as an effective means
of cell micromanipulation. To improve the survival rate and efficiency of injection, the …

Daniosense: automated high-throughput quantification of zebrafish larvae group movement

C Wang, M Tong, L Zhao, X Yu… - IEEE Transactions on …, 2021 - ieeexplore.ieee.org
The capability to obtain detailed motility information of model organisms is fundamental to
reveal their functional and social behavior characteristics. Zebrafish is a powerful vertebrate …

Automatic High-Throughput Injection System for Zebrafish Larvae Based on Precise Positioning of Injection Target

L Li, C Wang, H Gong, R Liu, Y Wang… - IEEE Transactions …, 2023 - ieeexplore.ieee.org
Zebrafish microinjection is widely used in vascular biology, neurology, and other research
areas. The microinjection of zebrafish larvae is a complicated 3D task because zebrafish …