The most lethal form of brain cancer, glioblastoma multiforme, is characterized by rapid growth and invasion facilitated by cell migration and degradation of the extracellular matrix …
Introduction to Mathematical Oncology presents biologically well-motivated and mathematically tractable models that facilitate both a deep understanding of cancer biology …
S Angeli, KE Emblem, P Due-Tonnessen… - NeuroImage: Clinical, 2018 - Elsevier
Previous studies to simulate brain tumor progression, often investigate either temporal changes in cancer cell density or the overall tissue-level growth of the tumor mass. Here, we …
Glioblastoma (GBM), the most aggressive brain tumor in human patients, is decidedly heterogeneous and highly vascularized. Glioma stem/initiating cells (GSC) are found to play …
Abstract Five immunocompetent C57BL/6-cBrd/cBrd/Cr (albino C57BL/6) mice were injected with GL261-luc2 cells, a cell line sharing characteristics of human glioblastoma multiforme …
A Nousi, MT Søgaard, M Audoin, L Jauffred - Biochemistry and Biophysics …, 2021 - Elsevier
Cell migration is a fundamental characteristic of vital processes such as tissue morphogenesis, wound healing and immune cell homing to lymph nodes and inflamed or …
Glioblastoma multiforme is a deadly brain cancer in which tumor cells excessively proliferate and migrate. The first mathematical models of the spread of gliomas featured reaction …
Glioblastoma multiforme is an aggressive brain cancer that is extremely fatal. It is characterized by both proliferation and large amounts of migration, which contributes to the …
A multiscale mathematical model for glioma cell migration and proliferation is proposed, taking into account a possible therapeutic approach. Starting with the description of …