The neurobiology of stress: Vulnerability, resilience, and major depression
H Akil, EJ Nestler - Proceedings of the National Academy of …, 2023 - National Acad Sciences
Over the past few years, the perceived level of psychological stress has risen dramatically
across the globe due to a combination of events including the long-lasting Covid-19 …
across the globe due to a combination of events including the long-lasting Covid-19 …
Multi-omics analysis of the molecular response to glucocorticoids-insights into shared genetic risk from psychiatric to medical disorders
J Knauer-Arloth, A Hryhorzhevska, EB Binder - medRxiv, 2023 - medrxiv.org
Background Glucocorticoids play a crucial role as mediators of negative health effects
associated with chronic stress, including increased risk for psychiatric disorders as well as …
associated with chronic stress, including increased risk for psychiatric disorders as well as …
Elevated glucocorticoid exposure during development alters behaviors and primes transcriptional responses to stress in adult zebrafish
Chronic or severe stress during development increases risk of adult diseases in humans.
One putative mechanism involves priming of stress-sensitive gene networks by early life …
One putative mechanism involves priming of stress-sensitive gene networks by early life …
Human cortical neurogenesis is altered via glucocorticoid-mediated regulation of ZBTB16 expression
Glucocorticoids are important for proper organ maturation, and their levels are tightly
regulated during development. Here, we use human cerebral organoids and mice to study …
regulated during development. Here, we use human cerebral organoids and mice to study …