Optimization of the polishing process by integrating experimental design and high-throughput screening
M Song, W Cao, Q Liu - Biochemical Engineering Journal, 2024 - Elsevier
Complex bispecific antibody formats tend to form more product-related impurities than
monoclonal antibodies. The primary constraints are yield and purity in the polishing stage …
monoclonal antibodies. The primary constraints are yield and purity in the polishing stage …
A versatile multimodal chromatography strategy to rapidly purify protein nanostructures assembled in cell lysates
DL Winter, H Lebhar, JB McCluskey… - Journal of …, 2023 - Springer
Background Protein nanostructures produced through the self-assembly of individual
subunits are attractive scaffolds to attach and position functional molecules for applications …
subunits are attractive scaffolds to attach and position functional molecules for applications …